Antioxidant and hepatoprotective activities of Dicoma anomala Sond. aqueous root extract against carbon tetrachloride-induced liver damage in Wistar rats

• Published in: Journal of traditional Chinese medicine Vol. 36; no. 4; p. 504
• Main Authors: Balogun, F O, Ashafa, A O T
• Format: Journal Article
• Language: English
• Published: China 01.08.2016
• Subjects: Alanine Transaminase - metabolism; Animals; Antioxidants - metabolism; Aspartate Aminotransferases - metabolism; Asteraceae - chemistry; Carbon Tetrachloride - adverse effects; Chemical and Drug Induced Liver Injury - drug therapy; Drugs, Chinese Herbal - administration & dosage; Female; Humans; Liver - drug effects; Liver - enzymology; Male; Plant Roots - chemistry; Protective Agents - administration & dosage; Rats; Rats, Wistar; Superoxide Dismutase - metabolism

To evaluates the antioxidant and hepatoprotective potentials of Dicoma anomala Sond. (Asteraceae) on body weight, feed and water intake, biochemical parameters and organ histology. Various concentrations (1.56-25 μg/mL) were used in the in vitro assays 1,1-diphenyl-2-picryl hydrazyl (DPPH, superoxid...