A Comparison of Three-Layer and Single-Layer Small Vascular Grafts Manufactured via the Roto-Evaporation Method

• Published in: Polymers Vol. 16; no. 10; p. 1314
• Main Authors: Zumbardo-Bacelis, Gualberto Antonio, Peponi, Laura, Vargas-Coronado, Rossana Faride, Rodríguez-Velázquez, Eustolia, Alatorre-Meda, Manuel, Chevallier, Pascale, Copes, Francesco, Mantovani, Diego, Abraham, Gustavo A, Cauich-Rodríguez, Juan Valerio
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.05.2024
• Subjects: Analysis; Ascorbic acid; Biocompatibility; biomedical applications; Biomedical materials; burst pressure; Bursting strength; Capitation; Cardiovascular disease; Chemical synthesis; Coagulation; compliance; Coronary vessels; COVID-19; Evaporation; Fibroblasts; Fourier transforms; Grafting; Heart surgery; Hyperplasia; Identification and classification; Lysine; mechanical properties; Methods; Polyethylene terephthalate; Polymers; Polyurethane; Polyurethane resins; Polyurethanes; Properties; roto-evaporation; Spectrum analysis; Tensile strength; Thrombosis; vascular graft; Vascular grafts; Vein & artery diseases; Canada; Mexico; Argentina; United States > US; burst pressure; vascular graft; roto-evaporation; biomedical applications; compliance; mechanical properties

This study used the roto-evaporation technique to engineer a 6 mm three-layer polyurethane vascular graft (TVG) that mimics the architecture of human coronary artery native vessels. Two segmented polyurethanes were synthesized using lysine (SPUUK) and ascorbic acid (SPUAA), and the resulting materia...