Exploring the Expression and Function of T Cell Surface Markers Identified through Cellular Indexing of Transcriptomes and Epitopes by Sequencing

• Published in: Yonsei medical journal Vol. 65; no. 9; pp. 544 - 555
• Main Authors: Hwang, Joon Yeon, Kim, Youngtaek, Kim, Dong Kwon, Lee, Seul, Kang, Seong-san, Baek, Sujeong, Yang, Seung Min, Kim, Mi Hyun, Han, Heekyung, Jeong, Seong Su, Lee, Chai Young, Han, Yu Jin, Sohn, Jie-Ohn, Ye, Sang-Kyu, Pyo, Kyoung-Ho
• Format: Journal Article
• Language: English
• Published: Korea (South) Yonsei University College of Medicine 01.09.2024; 연세대학교의과대학
• Subjects: CD4-Positive T-Lymphocytes - metabolism; CD8-Positive T-Lymphocytes - immunology; CD8-Positive T-Lymphocytes - metabolism; Epitopes - genetics; Epitopes - immunology; Gene Expression Profiling - methods; Humans; Leukocytes, Mononuclear - metabolism; Original; RNA, Messenger - genetics; RNA, Messenger - metabolism; T-Lymphocytes - immunology; T-Lymphocytes - metabolism; Transcriptome; 의학일반; single-cell gene expression analysis; T-lymphocyte subsets; CITE-seq; transcriptome; proteome

By utilizing both protein and mRNA expression patterns, we can identify more detailed and diverse immune cells, providing insights into understanding the complex immune landscape in cancer ecosystems. This study was performed by obtaining publicly available Cellular Indexing of Transcriptomes and Ep...