The Effect of Copper on Endometrial Receptivity and Induction of Apoptosis on Decidualized Human Endometrial Stromal Cells

• Published in: Reproductive sciences (Thousand Oaks, Calif.) Vol. 25; no. 7; pp. 985 - 999
• Main Authors: Carrascosa, Jose P., Cotán, David, Jurado, Inmaculada, Oropesa-Ávila, Manuel, Sánchez-Martín, Pascual, Savaris, Ricardo F., Tan, Justin, Sánchez-Alcázar, Jose A., Tan, Seang L., Horcajadas, José Antonio
• Format: Journal Article
• Language: English
• Published: Los Angeles, CA SAGE Publications 01.07.2018; Springer International Publishing
• Subjects: Embryology; Medicine & Public Health; Obstetrics/Perinatology/Midwifery; Original Article; Reproductive Medicine; endometrial receptivity; endometrium; copper; IUD; apoptosis; decidualization; gene expression

Intrauterine devices (IUDs) have been widely used to prevent pregnancies with great efficacy during decades. It has been demonstrated that IUD alters the endometrial gene expression, but there is no scientific data about how copper, a metal commonly used in these devices, by itself, is able to influ...