Goblet cell carcinoid of the appendix

Twelve tumors of the appendix are described which show histologic features different from both ordinary carcinoid and adenocarcinoma. The principal cell type has a close resemblance to the normal goblet cell in the epithelium of the intestinal tract. Paneth's and argentaffin cells were present...

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Published inCancer Vol. 34; no. 2; pp. 338 - 344
Main Authors Subbuswamy, S. G., Gibbs, N. M., Ross, C. F., Morson, B. C.
Format Journal Article
LanguageEnglish
Published New York Wiley Subscription Services, Inc., A Wiley Company 01.08.1974
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Abstract Twelve tumors of the appendix are described which show histologic features different from both ordinary carcinoid and adenocarcinoma. The principal cell type has a close resemblance to the normal goblet cell in the epithelium of the intestinal tract. Paneth's and argentaffin cells were present in considerable numbers in some of these tumors. The histology and prognosis suggest a tumor of very low grade of malignancy, comparable with the behavior of argentaffin and non‐argentaffin carcinoid of the appendix. However, the histology is sufficiently distinctive to justify separate classification, and we therefore recommend the expression „goblet cell carcinoid”︁ of the appendix.
AbstractList Twelve tumors of the appendix are described which show histologic features different from both ordinary carcinoid and adenocarcinoma. The principal cell type has a close resemblance to the normal goblet cell in the epithelium of the intestinal tract. Paneth's and argentaffin cells were present in considerable numbers in some of these tumors. The histology and prognosis suggest a tumor of very low grade of malignancy, comparable with the behavior of argentaffin and non‐argentaffin carcinoid of the appendix. However, the histology is sufficiently distinctive to justify separate classification, and we therefore recommend the expression „goblet cell carcinoid”︁ of the appendix.
Author Subbuswamy, S. G.
Gibbs, N. M.
Ross, C. F.
Morson, B. C.
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References 1968; 21
1956; 9
Dische (10.1002/1097-0142(197408)34:2<338::AID-CNCR2820340218>3.0.CO;2-W-BIB1) 1968; 21
Sieracki (10.1002/1097-0142(197408)34:2<338::AID-CNCR2820340218>3.0.CO;2-W-BIB2) 1956; 9
References_xml – volume: 9
  start-page: 997
  year: 1956
  end-page: 1011
  article-title: Primary adenocarcinoma of the vermiform appendix
  publication-title: Cancer
– volume: 21
  start-page: 60
  year: 1968
  end-page: 66
  article-title: Argentaffin and non‐argentaffin carcinoid tumours of the appendix
  publication-title: J. Clin. Pathol.
– volume: 21
  start-page: 60
  year: 1968
  ident: 10.1002/1097-0142(197408)34:2<338::AID-CNCR2820340218>3.0.CO;2-W-BIB1
  publication-title: J. Clin. Pathol.
  doi: 10.1136/jcp.21.1.60
  contributor:
    fullname: Dische
– volume: 9
  start-page: 997
  year: 1956
  ident: 10.1002/1097-0142(197408)34:2<338::AID-CNCR2820340218>3.0.CO;2-W-BIB2
  publication-title: Cancer
  doi: 10.1002/1097-0142(195609/10)9:5<997::AID-CNCR2820090520>3.0.CO;2-W
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StartPage 338
SubjectTerms Adult
Aged
Appendiceal Neoplasms - classification
Appendiceal Neoplasms - diagnosis
Appendiceal Neoplasms - pathology
Appendix - pathology
Carcinoid Tumor - diagnosis
Carcinoid Tumor - pathology
Epithelial Cells
Female
Humans
Male
Middle Aged
Title Goblet cell carcinoid of the appendix
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