Global distribution of consanguinity and their impact on complex diseases: Genetic disorders from an endogamous population

• Published in: The Egyptian journal of medical human genetics Vol. 18; no. 4; pp. 315 - 320
• Main Authors: Bener, Abdulbari, Mohammad, Ramzi R.
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Elsevier B.V 01.10.2017; Egyptian Society of Human Genetics; Springer Nature B.V; SpringerOpen
• Subjects: Age; Asthma; Cancer; Cigarette smoking; Complex diseases; Confidence intervals; Consanguinity; Coronary artery disease; Counseling; Diabetes mellitus; Disease; Eye; Eye diseases; Genetic counseling; Genetic disorders; Genetic factors; Genetic screening; Global impact; Glucosephosphate dehydrogenase; Hearing; Heart diseases; Hereditary diseases; Inbreeding; Intestine; Marriage; Mental disorders; Mortality; Nurses; Population; Primary care; Religion; Risk factors; Sample size; Statistical analysis; Studies; Validity; Water pipes; Womens health; Middle East; Saudi Arabia; Morocco; Arab countries; Qatar; Jordan (country); Oman; Yemen; Complex diseases; Inbreeding; Consanguinity; Global impact; Counseling

Marriage between close relatives has been practised globally since the early existence of human society. The role of consanguinity and inbreeding affecting human health is a topic of great interest in medical genetics. The objective of the study was to investigate the extent of consanguinity and its...