Hemodynamic responses to beta-adrenergic blockade with metoprolol and pindolol after coronary artery bypass surgery

• Published in: Chest Vol. 83; no. 5; p. 739
• Main Authors: Salmenperä, M, Yrjölä, H, Heikkilä, J
• Format: Journal Article
• Language: English
• Published: United States 01.05.1983
• Subjects: Adult; Body Temperature - drug effects; Cardiac Output - drug effects; Coronary Artery Bypass; Electrocardiography; Heart Rate - drug effects; Hemodynamics - drug effects; Humans; Metoprolol - pharmacology; Middle Aged; Oxygen Consumption - drug effects; Pindolol - pharmacology; Postoperative Care; Propanolamines - pharmacology; Random Allocation; Receptors, Adrenergic - drug effects; Receptors, Adrenergic, beta - drug effects; Vascular Resistance - drug effects

Varying ancillary properties of beta-adrenergic blocking drugs, such as intrinsic sympathomimetic activity or beta 1-selectivity, are known to evoke different hemodynamic effects. These differences may be relevant during hemodynamically unstable conditions. Twenty patients undergoing elective corona...