Interleukin-17 and Kidney Allograft Outcome

• Published in: Transplantation proceedings Vol. 41; no. 5; pp. 1562 - 1564
• Main Authors: Crispim, J.C.O, Grespan, R, Martelli-Palomino, G, Rassi, D.M, Costa, R.S, Saber, L.T, Cunha, F.Q, Donadi, E.A
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier Inc 01.06.2009; Elsevier
• Subjects: Adult; Animals; Biological and medical sciences; Biomarkers - blood; Biopsy; Female; Fundamental and applied biological sciences. Psychology; Fundamental immunology; Graft Rejection - blood; Graft Rejection - immunology; Humans; Immunosuppressive Agents - therapeutic use; Interleukin-17 - blood; Male; Medical sciences; Mice; Middle Aged; Reference Values; Surgery; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Tissue, organ and graft immunology; Medicine; Prognosis; Treatment; Urinary system; Surgery; Evolution; Graft; Transplantation; Homotransplantation; Interleukin 17; Kidney

Abstract Acute rejection episodes (ARE) are important complications that involve the interplay between mechanisms that maintain graft tolerance and promote rejection. The proinflammatory cytokine interleukin-17 (IL-17) has been implicated in many conditions in humans and mice. In kidney transplant p...