Changes in the Association Between Diagnostic Testing Method, Polymerase Chain Reaction Ribotype, and Clinical Outcomes From Clostridioides difficile Infection: One Institution’s Experience

• Published in: Clinical infectious diseases Vol. 73; no. 9; pp. e2883 - e2889
• Main Authors: Menon, Anitha, Perry, D Alex, Motyka, Jonathan, Weiner, Shayna, Standke, Alexandra, Penkevich, Aline, Keidan, Micah, Young, Vincent B, Rao, Krishna
• Format: Journal Article
• Language: English
• Published: US Oxford University Press 02.11.2021
• Subjects: Bacterial Toxins - genetics; Clostridioides; Clostridioides difficile - genetics; Clostridium Infections - diagnosis; Clostridium Infections - epidemiology; Feces; Humans; Online only; Polymerase Chain Reaction; Ribotyping; molecular epidemiology; diagnostic testing methods; toxins; infection prevention; C difficile

Abstract Background In Clostridioides difficile infection (CDI), the relationship between clinical, microbial, and temporal/epidemiological trends, disease severity and adverse outcomes is incompletely understood. In a follow-up to our study from 2010–2013, we evaluate stool toxin levels and C. diff...