Value of [18F]FDG PET radiomic features and VEGF expression in predicting pelvic lymphatic metastasis and their potential relationship in early-stage cervical squamous cell carcinoma

• Published in: European journal of radiology Vol. 106; pp. 160 - 166
• Main Authors: Li, Kexin, Sun, Hongzan, Lu, Zaiming, Xin, Jun, Zhang, Le, Guo, Yan, Guo, Qiyong
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier B.V 01.09.2018
• Subjects: 18F-fluorodeoxyglucose positron emission; Adult; Aged; Carcinoma, Squamous Cell - metabolism; Carcinoma, Squamous Cell - pathology; Cervical squamous cell carcinomas; Female; Fluorodeoxyglucose F18 - metabolism; Humans; Intratumor heterogeneity; Lymph Nodes - diagnostic imaging; Lymph Nodes - pathology; Lymphatic Metastasis; Middle Aged; Pelvis; Positron-Emission Tomography - methods; Predictive Value of Tests; Radiomics; Radiopharmaceuticals; Reproducibility of Results; Retrospective Studies; ROC Curve; Tomography; Uterine Cervical Neoplasms - metabolism; Uterine Cervical Neoplasms - pathology; Vascular Endothelial Growth Factor A - metabolism; Cervical squamous cell carcinomas; Tomography; Lymphatic metastasis; Intratumor heterogeneity; 18F-fluorodeoxyglucose positron emission; Radiomics; F-fluorodeoxyglucose positron emission

The purpose of this study was to explore the value of 2-deoxy-2-[18F]fluoro-d-glucose positron emission tomography/computed tomography ([18F]FDG PET/CT) radiomic features combined with vascular endothelial growth factor (VEGF) expression in predicting pelvic lymphatic metastasis in patients with ear...