Proteomic analysis of urine reveals biomarkers for the diagnosis and phenotyping of abdominal-type Henoch-Schonlein purpura

• Published in: Translational pediatrics Vol. 10; no. 3; pp. 510 - 524
• Main Authors: Jia, Lulu, Wu, Jianqiang, Wei, Jing, Du, Lina, Wang, Panpan, Zhang, Yanju, Yu, Yuncui, Wang, Xiaoling, Yang, Yan, Gao, Youhe
• Format: Journal Article
• Language: English
• Published: China AME Publishing Company 01.03.2021
• Subjects: Original; precision treatment; Henoch-Schonlein purpura (HSP); proteomics; urine; biomarkers

Abdominal-type Henoch-Schonlein purpura (HSP) is a common refractory disease in children. Currently, no specific diagnostic biomarker is available for HSP. Children with abdominal type HSP were first diagnosed with three syndromes using Chinese traditional medicine. The urinary proteomes among the t...