Regional right ventricular function in rats: a novel magnetic resonance imaging method for measurement of right ventricular strain

• Published in: American journal of physiology. Heart and circulatory physiology Vol. 318; no. 1; pp. H143 - H153
• Main Authors: Espe, Emil K. S., Aronsen, Jan M., Nordén, Einar S., Zhang, Lili, Sjaastad, Ivar
• Format: Journal Article
• Language: English
• Published: United States American Physiological Society 01.01.2020
• Subjects: Anesthesia; Animals; Biomechanical Phenomena; Blood pressure; Cardiovascular diseases; Congestion; Congestive heart failure; Diastolic pressure; Disease Models, Animal; Heart Ventricles - diagnostic imaging; Heart Ventricles - physiopathology; Isoflurane; Magnetic resonance imaging; Magnetic Resonance Imaging, Cine; Male; Medical imaging; Myocardial Contraction; Myocardial infarction; Myocardial Infarction - diagnostic imaging; Myocardial Infarction - physiopathology; NMR; Nuclear magnetic resonance; Predictive Value of Tests; Proof of Concept Study; Pulmonary Circulation; Rats, Wistar; Reproducibility of Results; Rodents; Strain rate; Stress, Mechanical; Surgery; Ventricle; Ventricular Function, Left; Ventricular Function, Right; Ventricular Pressure; Ventricular Remodeling; strain; right ventricle; phase contrast; contractility; tissue phase mapping

The function of the right ventricle (RV) is linked to clinical outcome in many cardiovascular diseases, but its role in experimental heart failure remains largely unexplored due to difficulties in measuring RV function in vivo. We aimed to advance RV imaging by establishing phase-contrast MRI (PC-MR...