Dissecting lipid droplet biology with coherent Raman scattering microscopy

• Published in: Journal of cell science Vol. 135; no. 5
• Main Authors: Chen, Tao, Yavuz, Ahmet, Wang, Meng C.
• Format: Journal Article
• Language: English
• Published: England The Company of Biologists Ltd 01.03.2022
• Subjects: Biology; Imaging; Lipid Droplets; Lipids; Microscopy; Review; Spectrum Analysis, Raman; Coherent Raman scattering microscopy; Lipid droplet; Lipid metabolism; Label-free imaging; Genetic screens

Lipid droplets (LDs) are lipid-rich organelles universally found in most cells. They serve as a key energy reservoir, actively participate in signal transduction and dynamically communicate with other organelles. LD dysfunction has been associated with a variety of diseases. The content level, compo...