Increased use-dependent plasticity in chronic insomnia

• Published in: Sleep (New York, N.Y.) Vol. 37; no. 3; pp. 535 - 544
• Main Authors: Salas, Rachel E, Galea, Joseph M, Gamaldo, Alyssa A, Gamaldo, Charlene E, Allen, Richard P, Smith, Michael T, Cantarero, Gabriela, Lam, Barbara D, Celnik, Pablo A
• Format: Journal Article
• Language: English
• Published: United States Associated Professional Sleep Societies, LLC 01.03.2014
• Subjects: Aged; Case-Control Studies; Evoked Potentials, Motor; Female; GABAergic Neurons - metabolism; Glutamine - metabolism; Humans; Increased Use-Dependent Plasticity in Chronic Insomnia; Male; Memory - physiology; Middle Aged; Motor Skills - physiology; Neuronal Plasticity - physiology; Sleep - physiology; Sleep Initiation and Maintenance Disorders - physiopathology; Transcranial Magnetic Stimulation; plasticity; memory; transcranial magnetic stimulation; motor training; Insomnia

During normal sleep several neuroplasticity changes occur, some of which are considered to be fundamental to strengthen memories. Given the evidence linking sleep to neuroplasticity, it is conceivable that individuals with chronic sleep disruption, such as patients with chronic insomnia (CI), would...