Rapid, Sample-to-Answer Host Gene Expression Test to Diagnose Viral Infection

• Published in: Open forum infectious diseases Vol. 6; no. 11; p. ofz466
• Main Authors: Tsalik, Ephraim L, Khine, Ayeaye, Talebpour, Abdossamad, Samiei, Alaleh, Parmar, Vilcy, Burke, Thomas W, Mcclain, Micah T, Ginsburg, Geoffrey S, Woods, Christopher W, Henao, Ricardo, Alavie, Tino
• Format: Journal Article
• Language: English
• Published: United States Oxford University Press 01.11.2019
• Subjects: Editor's Choice; Major; molecular diagnostic techniques; virus diseases; infection; gene expression profiling; real-time polymerase chain reaction
• ISSN: 2328-8957; 2328-8957
• DOI: 10.1093/ofid/ofz466

Distinguishing bacterial, viral, or other etiologies of acute illness is diagnostically challenging with significant implications for appropriate antimicrobial use. Host gene expression offers a promising approach, although no clinically useful test has been developed yet to accomplish this. Here, Q...