Vaccines with MF59 adjuvant expand the antibody repertoire to target protective sites of pandemic avian H5N1 influenza virus - Khurana, Surender; Chearwae, Wanida; Castellino, Flora; Manischewitz, Jody; King, Lisa R; Honorkiewicz, Agnieszka; Rock, Michael T; Edwards, Kathryn M; Del Giudice, Giuseppe; Rappuoli, Rino; Golding, Hana (Science translational medicine, 2010)
Keywords: Adjuvants, Immunologic - administration & dosage; Adjuvants, Immunologic - pharmacology; Adsorption - drug effects; Animals; Antibodies, Monoclonal - immunology; Antibodies, Neutralizing - immunology; Antibodies, Viral - immunology; Antibody Formation - drug effects; Birds - immunology; Birds - virology; Disease Outbreaks - prevention & control; Epitopes - chemistry; Epitopes - immunology; Humans; Hydrogen-Ion Concentration - drug effects; Influenza A Virus, H5N1 Subtype - drug effects; Influenza A Virus, H5N1 Subtype - immunology; Influenza in Birds - epidemiology; Influenza in Birds - immunology; Influenza in Birds - prevention & control; Influenza in Birds - virology; Influenza Vaccines - immunology; Influenza, Human - epidemiology; Influenza, Human - immunology; Influenza, Human - prevention & control; Influenza, Human - virology; Kinetics; Models, Molecular; Peptide Library; Polysorbates - pharmacology; Protein Folding - drug effects; Protein Structure, Tertiary; Squalene - immunology; Squalene - pharmacology; Vaccination