Obstructive Sleep Apnea Impairs Postexercise Sympathovagal Balance in Patients with Metabolic Syndrome

• Published in: Sleep (New York, N.Y.) Vol. 38; no. 7; pp. 1059 - 1066
• Main Authors: Cepeda, Felipe X, Toschi-Dias, Edgar, Maki-Nunes, Cristiane, Rondon, Maria Urbana P B, Alves, Maria Janieire N N, Braga, Ana Maria F W, Martinez, Daniel G, Drager, Luciano F, Lorenzi-Filho, Geraldo, Negrao, Carlos E, Trombetta, Ivani C
• Format: Journal Article
• Language: English
• Published: United States Associated Professional Sleep Societies, LLC 01.07.2015
• Subjects: Adult; Cross-Sectional Studies; Exercise - physiology; Exercise Test; Female; Heart Rate - physiology; Humans; Male; Metabolic Syndrome - complications; Metabolic Syndrome - physiopathology; Middle Aged; OSA Impairs Sympathovagal Balance in Metabolic Syndrome; Polysomnography; Sleep Apnea, Obstructive - complications; Sleep Apnea, Obstructive - physiopathology; Sympathetic Nervous System - physiopathology; Vagus Nerve - physiology; muscle sympathetic nerve activity; heart rate variability; heart rate recovery

The attenuation of heart rate recovery after maximal exercise (ΔHRR) is independently impaired by obstructive sleep apnea (OSA) and metabolic syndrome (MetS). Therefore, we tested the hypotheses: (1) MetS + OSA restrains ΔHRR; and (2) Sympathetic hyperactivation is involved in this impairment. Cross...