Preparation and characterization of grafted imprinted monolith for capillary electrochromatography

• Published in: Electrophoresis Vol. 33; no. 19-20; pp. 3021 - 3027
• Main Authors: Wei, Ze-Hui, Mu, Li-Na, Pang, Qian-Qian, Huang, Yan-Ping, Liu, Zhao-Sheng
• Format: Journal Article
• Language: English
• Published: Germany Blackwell Publishing Ltd 01.10.2012
• Subjects: Amlodipine - chemistry; Amlodipine - isolation & purification; Capillary Electrochromatography - instrumentation; Capillary Electrochromatography - methods; CEC; Chiral separation; Graft polymerization; Hydrogen-Ion Concentration; Limit of Detection; Methacrylates - chemistry; Molecular Imprinting - methods; Molecularly imprinted polymer; Monolithic column; Reproducibility of Results; Stereoisomerism

In this paper, a molecularly imprinted polymer (MIP) coating grafted to a trimethylolpropane trimethacrylate (TRIM) core material for CEC was reported. The core monolith was prepared with a solution of 20% (w/w) TRIM in a mixture of porogen and a polymerization precursor, which can generate a stable...