TNF-α signalling and inflammation: interactions between old acquaintances

• Published in: Inflammation research Vol. 62; no. 7; pp. 641 - 651
• Main Authors: Zelova, Hana, Hosek, Jan
• Format: Journal Article
• Language: English
• Published: Basel SP Birkhäuser Verlag Basel 01.07.2013
• Subjects: Allergology; Biomedical and Life Sciences; Biomedicine; Dermatology; Humans; Immunology; Inflammation - immunology; Neurology; Pharmacology/Toxicology; Receptors, Tumor Necrosis Factor - immunology; Review; Rheumatology; Tumor Necrosis Factor-alpha - immunology; TNFR; Inflammation; TNF-α; Apoptosis; Cancer

Introduction Inflammation is a very important part of innate immunity and is regulated in many steps. One such regulating step is the cytokine network, where tumor necrosis factor α (TNF-α) plays one of the most important roles. Methods A PubMed and Web of Science databases search was performed for...