Outcome Prediction by Quantitative Right Ventricular Function Assessment in 575 Subjects Evaluated for Pulmonary Hypertension

• Published in: Circulation. Cardiovascular imaging Vol. 6; no. 5; pp. 711 - 721
• Main Authors: Fine, Nowell M., Chen, Libo, Bastiansen, Paul M., Frantz, Robert P., Pellikka, Patricia A., Oh, Jae K., Kane, Garvan C.
• Format: Journal Article
• Language: English
• Published: United States 01.09.2013
• Subjects: Adult; Aged; Arterial Pressure; Biomechanical Phenomena; Chi-Square Distribution; Echocardiography, Doppler; Feasibility Studies; Female; Humans; Hypertension, Pulmonary - complications; Hypertension, Pulmonary - diagnostic imaging; Hypertension, Pulmonary - mortality; Hypertension, Pulmonary - physiopathology; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Prospective Studies; Pulmonary Artery - diagnostic imaging; Pulmonary Artery - physiopathology; Stress, Mechanical; Time Factors; Ventricular Dysfunction, Right - diagnostic imaging; Ventricular Dysfunction, Right - etiology; Ventricular Dysfunction, Right - mortality; Ventricular Dysfunction, Right - physiopathology; Ventricular Function, Right; strain; speckle-tracking echocardiography; pulmonary hypertension; right ventricular function; survival

Although right ventricular (RV) dysfunction is a major determinant of outcome in patients with pulmonary hypertension (PH), the optimal measure of RV function is poorly defined. We hypothesized that RV strain measured by speckle-tracking echocardiography predicts outcome in PH over a broad range of...