Hyperplasia of jejunal smooth muscle in the myenterically denervated rat

• Published in: Cell and tissue research Vol. 253; no. 3; p. 609
• Main Authors: See, N A, Epstein, M L, Schultz, E, Pienkowski, T P, Bass, P
• Format: Journal Article
• Language: English
• Published: Germany 01.09.1988
• Subjects: Animals; Autoradiography; Cell Division; Hyperplasia - pathology; Hyperplasia - physiopathology; Jejunum - pathology; Male; Muscle Denervation - adverse effects; Muscle, Smooth - pathology; Rats; Rats, Inbred Strains; Thymidine

Application of a cationic surfactant, benzalkonium chloride, to the serosa of rat jejunum results in an increase in thickness of both longitudinal and circular smooth muscle layers. The increase in thickness is due primarily to an increase in the number of smooth muscle cells (hyperplasia). Little c...