Within-subject biological variation of activated partial thromboplastin time, prothrombin time, fibrinogen, factor VIII and von Willebrand factor in pregnant women

• Published in: Clinical chemistry and laboratory medicine Vol. 56; no. 8; pp. 1297 - 1308
• Main Authors: Kristoffersen, Ann Helen, Petersen, Per Hyltoft, Bjørge, Line, Røraas, Thomas, Sandberg, Sverre
• Format: Journal Article
• Language: English
• Published: Germany De Gruyter 26.07.2018; Walter De Gruyter & Company
• Subjects: Biological variation; blood coagulation tests; Coagulation; Coagulation factors; Fibrinogen; Genetic transformation; haemostasis; Health risk assessment; Mathematical analysis; multiples of median; Parameter estimation; Physiological effects; Physiology; Pregnancy; Prothrombin; Reagents; Steady state; Thromboplastin; Von Willebrand factor; multiples of median; biological variation; blood coagulation tests; haemostasis; pregnancy

During pregnancy, interpretation of results from coagulation parameters can be difficult as the physiological changes that occur may affect the biochemical parameters. The aim of this study was to describe the normal course of five coagulation parameters in healthy pregnancies, and to estimate the w...