Diagnostic Performance of Metagenomic Next-Generation Sequencing in Pediatric Patients: A Retrospective Study in a Large Children’s Medical Center

• Published in: Clinical chemistry (Baltimore, Md.) Vol. 68; no. 8; pp. 1031 - 1041
• Main Authors: Tao, Yue, Yan, Hui, Liu, Yujie, Zhang, Fang, Luo, Lijuan, Zhou, Yajuan, An, Kang, Yang, Ruwen, Yang, Bin, Xu, Teng, Xie, Li, Ren, Hong, Xu, Zhuoming, Cao, Qing, Mo, Xi
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 27.07.2022
• Subjects: fungal; metagenomic next-generation sequencing; children; infectious diseases; antimicrobial usage

Abstract Background Metagenomic next-generation sequencing (mNGS) has the potential to become a complementary, if not essential, test in some clinical settings. However, the clinical application of mNGS in a large population of children with various types of infectious diseases (IDs) has not been pr...