TNF-α antagonist improves oxidative stress and lipid disorders induced by scorpion venom in the intestinal tissue

• Published in: Acta tropica Vol. 185; pp. 307 - 313
• Main Authors: Saidoune-Malek, Imane, Ait-Lounis, Aouatef, Laraba-Djebari, Fatima
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.09.2018
• Subjects: Aah venom; Animals; Intestinal Mucosa - metabolism; Intestine tissue; Intestines - drug effects; Lipid metabolism; Lipid Metabolism - drug effects; Lipids - analysis; Mice; Mice, Inbred Strains; Oxidative stress; Oxidative Stress - drug effects; Scorpion Venoms - toxicity; TNF-α antagonist; Tumor Necrosis Factor-alpha - antagonists & inhibitors; Tumor Necrosis Factor-alpha - physiology; Intestine tissue; Oxidative stress; Lipid metabolism; Aah venom; TNF-α antagonist

[Display omitted] •TNF-α antagonist improves intestinal oxidative damage induced by Aah venom.•TNF-α antagonist improves intestinal cytotoxicity in Aah-envenomed mice.•TNF-α antagonist improves postprandial serum lipid in Aah-envenomed mice.•TNF-α antagonist improves intestinal lipid profile in Aah-...