Meta-Analysis of the Input and Disposition of Various Dosage Forms of Methylprednisolone in Healthy Subjects Utilizing a Physiologically Based Pharmacokinetic Model - Yu, Ruihong; Jusko, William J. (The AAPS journal, 2025)
Keywords: Administration, Oral; Analysis; Biological Availability; Corticosteroids; Esters; Generic drugs; Half-Life; Healthy Volunteers; Humans; Injections, Intramuscular; Liver; Methylprednisolone; Methylprednisolone - administration & dosage; Methylprednisolone - pharmacokinetics; Models, Biological; Phosphates; Tissue Distribution; methylprednisolone; pharmacokinetics; prodrug conversion; minimal physiologically based pharmacokinetic model (mPBPK model); human