Vitamin D: Methods of 25 hydroxyvitamin D analysis, targeting at risk populations and selecting thresholds of treatment

• Published in: Clinical biochemistry Vol. 45; no. 12; pp. 901 - 906
• Main Authors: Glendenning, Paul, Inderjeeth, Charles A.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.08.2012
• Subjects: 25OHD target of treatment; Animals; Biomarkers - blood; Biomarkers - urine; Blood Chemical Analysis - standards; Bone Density; Calcifediol - blood; Calcifediol - therapeutic use; Dietary Supplements; Humans; Methods of 25OHD analysis; Reference Standards; Reference Values; Vitamin D; Vitamin D Deficiency - blood; Vitamin D Deficiency - diagnosis; Vitamin D Deficiency - drug therapy; Vitamins - blood; Vitamins - therapeutic use; Vitamin D; Methods of 25OHD analysis; 25OHD target of treatment

Interest in vitamin D has intensified with the association of vitamin D deficiency (VDD) with many diseases. This review will outline the limitations of current 25 hydroxyvitamin D (25OHD) methods, the target treatment threshold, and review the classical (endocrine/bone) and non-classical (paracrine...