Vitamin D: Methods of 25 hydroxyvitamin D analysis, targeting at risk populations and selecting thresholds of treatment
Interest in vitamin D has intensified with the association of vitamin D deficiency (VDD) with many diseases. This review will outline the limitations of current 25 hydroxyvitamin D (25OHD) methods, the target treatment threshold, and review the classical (endocrine/bone) and non-classical (paracrine...
Saved in:
| Published in | Clinical biochemistry Vol. 45; no. 12; pp. 901 - 906 |
|---|---|
| Main Authors | , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Elsevier Inc
01.08.2012
|
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | Interest in vitamin D has intensified with the association of vitamin D deficiency (VDD) with many diseases. This review will outline the limitations of current 25 hydroxyvitamin D (25OHD) methods, the target treatment threshold, and review the classical (endocrine/bone) and non-classical (paracrine/non-bone) actions of vitamin D. Recent standardisation by the National Institutes of Standards and Technology and use of LC tandem mass methodology has reduced inter-method bias but insensitivity and imprecision of automated methods have challenged assay performance. Many diseases are associated with VDD but randomised clinical trial data demonstrating the benefit of un-activated sterol supplementation only exists for the prevention of falls and fractures. Consequently, 25OHD measurement should be restricted to high falls or fracture risk patients. Controversy regarding the 25OHD target of therapy requires consensus. Until resolved, widespread adoption of screening programmes and measurement of 25OHD in patients at risk of non-musculoskeletal disease is premature, costly and not supported by evidence. |
|---|---|
| AbstractList | Interest in vitamin D has intensified with the association of vitamin D deficiency (VDD) with many diseases. This review will outline the limitations of current 25 hydroxyvitamin D (25OHD) methods, the target treatment threshold, and review the classical (endocrine/bone) and non-classical (paracrine/non-bone) actions of vitamin D. Recent standardisation by the National Institutes of Standards and Technology and use of LC tandem mass methodology has reduced inter-method bias but insensitivity and imprecision of automated methods have challenged assay performance. Many diseases are associated with VDD but randomised clinical trial data demonstrating the benefit of un-activated sterol supplementation only exists for the prevention of falls and fractures. Consequently, 25OHD measurement should be restricted to high falls or fracture risk patients. Controversy regarding the 25OHD target of therapy requires consensus. Until resolved, widespread adoption of screening programmes and measurement of 25OHD in patients at risk of non-musculoskeletal disease is premature, costly and not supported by evidence. |
| Author | Glendenning, Paul Inderjeeth, Charles A. |
| Author_xml | – sequence: 1 givenname: Paul surname: Glendenning fullname: Glendenning, Paul email: Paul.Glendenning@health.wa.gov.au organization: Department of Core Clinical Pathology and Biochemistry, Royal Perth Hospital, Australia – sequence: 2 givenname: Charles A. surname: Inderjeeth fullname: Inderjeeth, Charles A. organization: School of Medicine and Pharmacology, University of Western Australia, Australia |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/22522083$$D View this record in MEDLINE/PubMed |
| BookMark | eNqNkE1v1DAQQC1URLeFv1C5Nw4k-GvjpDe0tBSpiAtwtRx70nib2Ivtbbv_vl62RRw5zYzmzYzmnaAjHzwgdE5JTQltPq5rMznfu2BGmGtGKKuJqAlhr9CCtpJXrOP8CC0IIV3VUUaO0UlK61Iy0TZv0DFjS8ZIyxfo4ZfLenYef77A3yCPwSYcBsyWeNzZGB539y99rL2edsmlDzjreAvZ-VusM44u3eFN2GwnnV3wqXAWJ5jA_CHyGCGNYTrszRF0nsHnt-j1oKcE757jKfp5dfljdV3dfP_ydfXppjJcylwxIQwzfU97CQb4shXQDIzLpaCisYJIbiTtBr1PerCaD6bVg6Wi7wknDeWn6P1h7yaG31tIWc0uGZgm7SFsk6KENU0rO9kUtDugJoaUIgxqE92s465Aau9drdU_3tXeuyJCFatl9uz5zLafwf6dfBFdgNUBgPLsvYOoknHgDVgXiyllg_uPM0-sRZ18 |
| CitedBy_id | crossref_primary_10_1177_201010581302200311 crossref_primary_10_1111_j_1445_5994_2012_02908_x crossref_primary_10_1016_j_clinbiochem_2012_05_028 crossref_primary_10_1210_er_2012_1071 crossref_primary_10_1016_S2213_8587_20_30380_6 crossref_primary_10_1097_MCO_0b013e328364ca96 crossref_primary_10_1016_j_fertnstert_2020_12_001 crossref_primary_10_1017_S000711451400186X crossref_primary_10_1136_bmjopen_2021_059075 crossref_primary_10_1002_jms_3522 crossref_primary_10_1016_j_clinbiochem_2015_11_022 crossref_primary_10_1515_cclm_2015_0781 crossref_primary_10_1053_j_jfas_2015_08_002 |
| Cites_doi | 10.1515/CCLM.2011.050 10.1258/acb.2007.007091 10.1016/S0140-6736(03)14636-3 10.1210/jcem-33-3-554 10.1210/jc.2006-0710 10.1515/CCLM.2011.072 10.1056/NEJM199803193381201 10.1006/abbi.1996.0213 10.1111/j.1365-2265.2009.03701.x 10.1016/j.autrev.2010.06.009 10.1016/j.amjmed.2003.12.029 10.1210/jc.2008-1832 10.1210/er.22.4.477 10.1373/clinchem.2005.052936 10.1056/NEJM199709043371003 10.1136/bmj.b3692 10.1258/acb.2008.008135 10.1002/jbmr.190 10.1016/j.bone.2009.07.015 10.1001/jama.291.16.1999 10.1258/000456303322326470 10.1002/ijc.25439 10.1093/rheumatology/kem240 10.1016/j.jphotobiol.2007.09.008 10.1210/jcem-33-6-992 10.1001/jama.2011.50 10.1080/07315724.2003.10719287 10.1007/s001980050162 10.1001/jama.2010.594 10.1002/jbmr.524 10.1001/archinternmed.2007.31 10.1074/jbc.M311473200 10.1210/jc.2011-0385 10.1111/j.1365-2265.2010.03821.x 10.1046/j.1365-2796.2001.00895.x 10.7326/0003-4819-149-4-200808190-00005 10.1046/j.1532-5415.2003.51510.x 10.1373/clinchem.2004.040683 10.1258/000456306775141650 10.1359/jbmr.080230 10.1002/(SICI)1097-4644(20000701)78:1<112::AID-JCB10>3.0.CO;2-7 10.1016/j.archger.2007.12.005 10.1373/clinchem.2010.152553 10.1111/j.1445-5994.2003.00484.x 10.1016/0003-2697(77)90648-0 10.1016/S0140-6736(74)92545-8 10.1093/ajcn/85.6.1586 10.1001/jama.294.18.2336 10.1093/ajcn/77.2.522 10.1056/NEJMoa032071 10.1359/jbmr.090728 10.1210/jc.2010-2202 10.1056/NEJM199212033272305 10.1007/s00198-010-1285-3 10.1186/1475-2891-10-46 10.1093/clinchem/24.2.287 10.1359/jbmr.070716 10.1016/S8756-3282(02)00866-9 10.1056/NEJMp1102022 10.1016/S0140-6736(74)91640-7 10.1038/ejcn.2011.118 10.1136/bmj.1.6163.589 10.1093/clinchem/31.11.1815 10.1016/S0140-6736(05)78933-9 10.1210/jc.2008-2786 10.1097/PAT.0b013e328346431c 10.1258/acb.2011.011018 |
| ContentType | Journal Article |
| Copyright | 2012 Crown Copyright © 2012. Published by Elsevier Inc. All rights reserved. |
| Copyright_xml | – notice: 2012 – notice: Crown Copyright © 2012. Published by Elsevier Inc. All rights reserved. |
| DBID | CGR CUY CVF ECM EIF NPM AAYXX CITATION 7X8 |
| DOI | 10.1016/j.clinbiochem.2012.04.002 |
| DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef MEDLINE - Academic |
| DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef MEDLINE - Academic |
| DatabaseTitleList | MEDLINE MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine Chemistry |
| EISSN | 1873-2933 |
| EndPage | 906 |
| ExternalDocumentID | 10_1016_j_clinbiochem_2012_04_002 22522083 S0009912012001683 |
| Genre | Journal Article Review |
| GroupedDBID | --- --K --M -~X .55 .GJ .~1 0R~ 1B1 1RT 1~. 1~5 29B 4.4 457 4G. 4R4 53G 5GY 5VS 6J9 7-5 71M 8P~ 9JM AACTN AAEDT AAEDW AAIAV AAIKJ AAKOC AALRI AAOAW AAQFI AAQXK AAXUO AAYJJ ABBQC ABFNM ABFRF ABGSF ABJNI ABLVK ABMAC ABMZM ABOCM ABUDA ABXDB ABYKQ ACDAQ ACGFO ACGFS ACIUM ACRLP ADBBV ADEZE ADMUD ADUVX AEBSH AEFWE AEHWI AEKER AENEX AFKWA AFTJW AFXIZ AGHFR AGRDE AGUBO AGYEJ AHHHB AHPSJ AIEXJ AIKHN AITUG AJBFU AJOXV AJRQY ALMA_UNASSIGNED_HOLDINGS AMFUW AMRAJ ANZVX ASPBG AVWKF AXJTR AZFZN BKOJK BLXMC BNPGV CS3 DOVZS DU5 EBS EFJIC EFLBG EJD EO8 EO9 EP2 EP3 F5P FDB FEDTE FGOYB FIRID FNPLU FYGXN G-2 G-Q G8K GBLVA HLW HVGLF HX~ HZ~ IHE J1W KOM LCYCR LX3 M41 MO0 N9A O-L O9- OAUVE OZT P-8 P-9 P2P PC. Q38 R2- RIG ROL RPZ SBG SDF SDG SDP SES SEW SPCBC SSH SSU SSZ T5K UNMZH WUQ X7M XPP YYP YYQ ZGI ZUP ~G- AAXKI ADVLN AFJKZ AKRWK CGR CUY CVF ECM EIF NPM AAYXX CITATION 7X8 |
| ID | FETCH-LOGICAL-c377t-244c2cbb1b7ece3584e6f23754146d4073c719fa073cbeda3fc8afd14bb030613 |
| IEDL.DBID | AIKHN |
| ISSN | 0009-9120 |
| IngestDate | Fri Oct 25 09:05:37 EDT 2024 Thu Sep 26 19:00:38 EDT 2024 Sat Sep 28 07:49:33 EDT 2024 Fri Feb 23 02:36:35 EST 2024 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 12 |
| Keywords | Vitamin D Methods of 25OHD analysis 25OHD target of treatment |
| Language | English |
| License | Crown Copyright © 2012. Published by Elsevier Inc. All rights reserved. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c377t-244c2cbb1b7ece3584e6f23754146d4073c719fa073cbeda3fc8afd14bb030613 |
| Notes | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 |
| PMID | 22522083 |
| PQID | 1026687976 |
| PQPubID | 23479 |
| PageCount | 6 |
| ParticipantIDs | proquest_miscellaneous_1026687976 crossref_primary_10_1016_j_clinbiochem_2012_04_002 pubmed_primary_22522083 elsevier_sciencedirect_doi_10_1016_j_clinbiochem_2012_04_002 |
| PublicationCentury | 2000 |
| PublicationDate | August 2012 2012-Aug 2012-8-00 20120801 |
| PublicationDateYYYYMMDD | 2012-08-01 |
| PublicationDate_xml | – month: 08 year: 2012 text: August 2012 |
| PublicationDecade | 2010 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States |
| PublicationTitle | Clinical biochemistry |
| PublicationTitleAlternate | Clin Biochem |
| PublicationYear | 2012 |
| Publisher | Elsevier Inc |
| Publisher_xml | – name: Elsevier Inc |
| References | Stepman, Vanderroost, Van Uytfanghe, Thienpont (bb0335) 2011; 57 Priemel, von Domarus, Klatte, Kessler, Schlie, Meier (bb0055) 2010; 25 Gandini, Boniol, Haukka, Byrnes, Cox, Sneyd (bb0230) 2011; 128 Glendenning (bb0285) 2003; 77 Connell, Jenkins, Black, Pasco, Kotowicz, Schneider (bb0305) 2011; 43 Kamao, Tatematsu, Hatakeyama, Sakaki, Sawada, Inouye (bb0340) 2004; 279 Heaney, Dowell, Hale, Bendich (bb0060) 2003; 22 Roth, Zahn, Alkier, Schmidt (bb0290) 2001; 47 Maunsell, Wright, Rainbow (bb0365) 2005; 51 Bischoff-Ferrari, Dietrich, Orav, Dawson-Hughes (bb0100) 2004; 116 Shah, James, Barker, Petroczi, Naughton (bb0370) 2011; 10 Jesudason, Need, Horowitz, O'Loughlin, Morris, Nordin (bb0095) 2002; 31 Roth, Schmidt-Gayk, Weber, Niederau (bb0380) 2008; 45 Chapuy, Arlot, Duboeuf, Brun, Crouzet, Arnaud (bb0005) 1992; 327 Chlebowski, Wactawski-Wende, Ritenbaugh, Hubbell, Ascensao, Rodabough (bb0245) 2004; 350 Glendenning, Chew, Seymour, Gillett, Goldswain, Inderjeeth (bb0330) 2009; 45 Kuchuk, Pluijm, van Schoor, Looman, Smit, Lips (bb0090) 2009; 94 Belsey, Deluca, Potts (bb0260) 1971; 33 Bischoff-Ferrari, Dawson-Hughes, Willett, Staehelin, Bazemore, Zee (bb0020) 2004; 291 Prince, Austin, Devine, Dick, Bruce, Zhu (bb0115) 2008; 168 Nuti, Martini, Valenti, Giovani, Salvadori, Avanzati (bb0190) 2001; 250 Kimlin, Harrison, Nowak, Moore, Brodie, Lang (bb0175) 2007; 89 Stepman, Vanderroost, Stockl, Thienpont (bb0360) 2011; 49 Baker, McDonnell, Peacock, Nordin (bb0045) 1979; 1 Holick, Binkley, Bischoff-Ferrari, Gordon, Hanley, Heaney (bb0125) 2011; 96 Smith, Anderson, Raphael, Maslin, Crozier, Cooper (bb0150) 2007; 46 Haddad, Chyu (bb0255) 1971; 33 Bischoff-Ferrari, Dawson-Hughes, Staehelin, Orav, Stuck, Theiler (bb0120) 2009; 339 Steingrimsdottir, Gunnarsson, Indridason, Franzson, Sigurdsson (bb0080) 2005; 294 Eisman, Shepard, DeLuca (bb0265) 1977; 80 Mitri, Muraru, Pittas (bb0225) 2011; 65 Lips, Bouillon, van Schoor, Vanderschueren, Verschueren, Kuchuk (bb0155) 2010; 73 Cavalier, Huberty, Cormier, Souberbielle (bb0280) 2011; 26 Bjorkman, Sorva, Tilvis (bb0085) 2009; 48 Fleet, Bradley, Reddy, Ray, Wood (bb0355) 1996; 329 Manson, Mayne, Clinton (bb0240) 2011; 364 Aaron, Gallagher, Anderson, Stasiak, Longton, Nordin (bb0035) 1974; 1 Glendenning, Zhu, Inderjeeth, Howat, Lewis, Prince (bb0140) 2011; 27 Glendenning (bb0215) 2003; 33 Carter, Carter, Jones, Berry (bb0310) 2004; 50 Lips, Chapuy, Dawson-Hughes, Pols, Holick (bb0075) 1999; 9 Cauley, Lacroix, Wu, Horwitz, Danielson, Bauer (bb0110) 2008; 149 Slomski (bb0135) 2011; 305 Glendenning, Noble, Taranto, Musk, McGuiness, Goldswain (bb0295) 2003; 40 Dawson-Hughes, Harris, Krall, Dallal (bb0010) 1997; 337 Ensrud, Taylor, Paudel, Cauley, Cawthon, Cummings (bb0105) 2009; 94 Souberbielle, Body, Lappe, Plebani, Shoenfeld, Wang (bb0235) 2010; 9 Lips (bb0025) 2007; 22 Thomas, Lloyd-Jones, Thadhani, Shaw, Deraska, Kitch (bb0195) 1998; 338 Lappe, Travers-Gustafson, Davies, Recker, Heaney (bb0250) 2007; 85 Malabanan, Veronikis, Holick (bb0070) 1998; 351 Seymour, Glendenning (bb0210) 2005; 183 Sanders, Stuart, Williamson, Simpson, Kotowicz, Young (bb0145) 2010; 303 Grover, Morley (bb0170) 2001; 175 McCombie, Mason, Damian (bb0180) 2009; 190 Jones (bb0270) 1978; 24 Dawson-Hughes, Mithal, Bonjour, Boonen, Burckhardt, Fuleihan (bb0130) 2010; 21 Inderjeeth, Glennon, Petta, Soderstrom, Boyatzis, Tapper (bb0015) 2007; 120 Wharton, Rickets (bb0030) 2003; 362 Hansen, Jones, Lindstrom, Davis, Engelke, Shafer (bb0065) 2008; 23 Sambrook, Cameron, Cumming, Lord, Schwarz, Trube (bb0165) 2002; 176 Carter, Jones (bb0375) 2009; 46 Singh, Taylor, Reddy, Grebe (bb0345) 2006; 91 Boudville, Inderjeeth, Elder, Glendenning (bb0200) 2010; 73 Vasikaran, Sturdy, Musk, Flicker (bb0220) 2000; 172 Cluse, Fudge, Whiting, McWhinney, Parkinson, O'Loughlin (bb0300) 2012; 49 Grethen, McClintock, Gupta, Jones, Cacucci, Diaz (bb0185) 2011; 96 Harant, Spinner, Reddy, Lindley (bb0350) 2000; 78 Cavalier, Wallace, Carlisi, Chapelle, Delanaye, Souberbielle (bb0315) 2011; 49 Hollis, Napoli (bb0275) 1985; 31 Flicker, Mead, MacInnis, Nowson, Scherer, Stein (bb0160) 2003; 51 Aaron, Gallagher, Nordin (bb0040) 1974; 2 Glendenning, Taranto, Noble, Musk, Hammond, Goldswain (bb0325) 2006; 43 Glendenning (bb0320) 2002; 176 Lips (bb0050) 2001; 22 Noble, McGuiness, Glendenning (bb0205) 2002; 177 Bischoff-Ferrari (10.1016/j.clinbiochem.2012.04.002_bb0020) 2004; 291 Steingrimsdottir (10.1016/j.clinbiochem.2012.04.002_bb0080) 2005; 294 Grover (10.1016/j.clinbiochem.2012.04.002_bb0170) 2001; 175 Lappe (10.1016/j.clinbiochem.2012.04.002_bb0250) 2007; 85 Aaron (10.1016/j.clinbiochem.2012.04.002_bb0040) 1974; 2 Haddad (10.1016/j.clinbiochem.2012.04.002_bb0255) 1971; 33 Connell (10.1016/j.clinbiochem.2012.04.002_bb0305) 2011; 43 Kuchuk (10.1016/j.clinbiochem.2012.04.002_bb0090) 2009; 94 Dawson-Hughes (10.1016/j.clinbiochem.2012.04.002_bb0130) 2010; 21 McCombie (10.1016/j.clinbiochem.2012.04.002_bb0180) 2009; 190 Chlebowski (10.1016/j.clinbiochem.2012.04.002_bb0245) 2004; 350 Bischoff-Ferrari (10.1016/j.clinbiochem.2012.04.002_bb0100) 2004; 116 Sambrook (10.1016/j.clinbiochem.2012.04.002_bb0165) 2002; 176 Glendenning (10.1016/j.clinbiochem.2012.04.002_bb0215) 2003; 33 Noble (10.1016/j.clinbiochem.2012.04.002_bb0205) 2002; 177 Souberbielle (10.1016/j.clinbiochem.2012.04.002_bb0235) 2010; 9 Bischoff-Ferrari (10.1016/j.clinbiochem.2012.04.002_bb0120) 2009; 339 Grethen (10.1016/j.clinbiochem.2012.04.002_bb0185) 2011; 96 Hollis (10.1016/j.clinbiochem.2012.04.002_bb0275) 1985; 31 Shah (10.1016/j.clinbiochem.2012.04.002_bb0370) 2011; 10 Singh (10.1016/j.clinbiochem.2012.04.002_bb0345) 2006; 91 Cavalier (10.1016/j.clinbiochem.2012.04.002_bb0315) 2011; 49 Vasikaran (10.1016/j.clinbiochem.2012.04.002_bb0220) 2000; 172 Cluse (10.1016/j.clinbiochem.2012.04.002_bb0300) 2012; 49 Malabanan (10.1016/j.clinbiochem.2012.04.002_bb0070) 1998; 351 Kamao (10.1016/j.clinbiochem.2012.04.002_bb0340) 2004; 279 Stepman (10.1016/j.clinbiochem.2012.04.002_bb0335) 2011; 57 Baker (10.1016/j.clinbiochem.2012.04.002_bb0045) 1979; 1 Heaney (10.1016/j.clinbiochem.2012.04.002_bb0060) 2003; 22 Belsey (10.1016/j.clinbiochem.2012.04.002_bb0260) 1971; 33 Jones (10.1016/j.clinbiochem.2012.04.002_bb0270) 1978; 24 Cavalier (10.1016/j.clinbiochem.2012.04.002_bb0280) 2011; 26 Glendenning (10.1016/j.clinbiochem.2012.04.002_bb0330) 2009; 45 Gandini (10.1016/j.clinbiochem.2012.04.002_bb0230) 2011; 128 Cauley (10.1016/j.clinbiochem.2012.04.002_bb0110) 2008; 149 Aaron (10.1016/j.clinbiochem.2012.04.002_bb0035) 1974; 1 Priemel (10.1016/j.clinbiochem.2012.04.002_bb0055) 2010; 25 Glendenning (10.1016/j.clinbiochem.2012.04.002_bb0325) 2006; 43 Fleet (10.1016/j.clinbiochem.2012.04.002_bb0355) 1996; 329 Wharton (10.1016/j.clinbiochem.2012.04.002_bb0030) 2003; 362 Roth (10.1016/j.clinbiochem.2012.04.002_bb0290) 2001; 47 Lips (10.1016/j.clinbiochem.2012.04.002_bb0025) 2007; 22 Prince (10.1016/j.clinbiochem.2012.04.002_bb0115) 2008; 168 Manson (10.1016/j.clinbiochem.2012.04.002_bb0240) 2011; 364 Kimlin (10.1016/j.clinbiochem.2012.04.002_bb0175) 2007; 89 Boudville (10.1016/j.clinbiochem.2012.04.002_bb0200) 2010; 73 Maunsell (10.1016/j.clinbiochem.2012.04.002_bb0365) 2005; 51 Roth (10.1016/j.clinbiochem.2012.04.002_bb0380) 2008; 45 Glendenning (10.1016/j.clinbiochem.2012.04.002_bb0285) 2003; 77 Chapuy (10.1016/j.clinbiochem.2012.04.002_bb0005) 1992; 327 Lips (10.1016/j.clinbiochem.2012.04.002_bb0050) 2001; 22 Jesudason (10.1016/j.clinbiochem.2012.04.002_bb0095) 2002; 31 Holick (10.1016/j.clinbiochem.2012.04.002_bb0125) 2011; 96 Stepman (10.1016/j.clinbiochem.2012.04.002_bb0360) 2011; 49 Bjorkman (10.1016/j.clinbiochem.2012.04.002_bb0085) 2009; 48 Inderjeeth (10.1016/j.clinbiochem.2012.04.002_bb0015) 2007; 120 Dawson-Hughes (10.1016/j.clinbiochem.2012.04.002_bb0010) 1997; 337 Smith (10.1016/j.clinbiochem.2012.04.002_bb0150) 2007; 46 Nuti (10.1016/j.clinbiochem.2012.04.002_bb0190) 2001; 250 Ensrud (10.1016/j.clinbiochem.2012.04.002_bb0105) 2009; 94 Slomski (10.1016/j.clinbiochem.2012.04.002_bb0135) 2011; 305 Carter (10.1016/j.clinbiochem.2012.04.002_bb0310) 2004; 50 Glendenning (10.1016/j.clinbiochem.2012.04.002_bb0140) 2011; 27 Seymour (10.1016/j.clinbiochem.2012.04.002_bb0210) 2005; 183 Hansen (10.1016/j.clinbiochem.2012.04.002_bb0065) 2008; 23 Harant (10.1016/j.clinbiochem.2012.04.002_bb0350) 2000; 78 Flicker (10.1016/j.clinbiochem.2012.04.002_bb0160) 2003; 51 Lips (10.1016/j.clinbiochem.2012.04.002_bb0155) 2010; 73 Carter (10.1016/j.clinbiochem.2012.04.002_bb0375) 2009; 46 Lips (10.1016/j.clinbiochem.2012.04.002_bb0075) 1999; 9 Sanders (10.1016/j.clinbiochem.2012.04.002_bb0145) 2010; 303 Thomas (10.1016/j.clinbiochem.2012.04.002_bb0195) 1998; 338 Eisman (10.1016/j.clinbiochem.2012.04.002_bb0265) 1977; 80 Mitri (10.1016/j.clinbiochem.2012.04.002_bb0225) 2011; 65 Glendenning (10.1016/j.clinbiochem.2012.04.002_bb0320) 2002; 176 Glendenning (10.1016/j.clinbiochem.2012.04.002_bb0295) 2003; 40 |
| References_xml | – volume: 89 start-page: 139 year: 2007 end-page: 147 ident: bb0175 article-title: Does a high UV environment ensure adequate vitamin D status? publication-title: J Photochem Photobiol B contributor: fullname: Lang – volume: 294 start-page: 2336 year: 2005 end-page: 2341 ident: bb0080 article-title: Relationship between serum parathyroid hormone levels, vitamin D sufficiency, and calcium intake publication-title: JAMA contributor: fullname: Sigurdsson – volume: 10 start-page: 46 year: 2011 ident: bb0370 article-title: Misleading measures in Vitamin D analysis: a novel LC–MS/MS assay to account for epimers and isobars publication-title: Nutr J contributor: fullname: Naughton – volume: 22 start-page: 477 year: 2001 end-page: 501 ident: bb0050 article-title: Vitamin D deficiency and secondary hyperparathyroidism in the elderly: consequences for bone loss and fractures and therapeutic implications publication-title: Endocr Rev contributor: fullname: Lips – volume: 176 start-page: 560 year: 2002 ident: bb0165 article-title: Vitamin D deficiency is common in frail institutionalised older people in northern Sydney publication-title: MJA contributor: fullname: Trube – volume: 91 start-page: 3055 year: 2006 end-page: 3061 ident: bb0345 article-title: C-3 epimers can account for a significant proportion of total circulating 25-hydroxyvitamin D in infants, complicating accurate measurement and interpretation of vitamin D status publication-title: J Clin Endocrinol Metab contributor: fullname: Grebe – volume: 279 start-page: 15897 year: 2004 end-page: 15907 ident: bb0340 article-title: C-3 epimerization of vitamin D3 metabolites and further metabolism of C-3 epimers: 25-hydroxyvitamin D3 is metabolized to 3-epi-25-hydroxyvitamin D3 and subsequently metabolized through C-1alpha or C-24 hydroxylation publication-title: J Biol Chem contributor: fullname: Inouye – volume: 351 start-page: 805 year: 1998 end-page: 806 ident: bb0070 article-title: Redefining vitamin D insufficiency publication-title: Lancet contributor: fullname: Holick – volume: 77 start-page: 522 year: 2003 end-page: 523 ident: bb0285 article-title: Issues of standardization and assay-specific clinical decision limits for the measurement of 25-hydroxyvitamin D publication-title: Am J Clin Nutr contributor: fullname: Glendenning – volume: 31 start-page: 626 year: 2002 end-page: 630 ident: bb0095 article-title: Relationship between serum 25-hydroxyvitamin D and bone resorption markers in vitamin D insufficiency publication-title: Bone contributor: fullname: Nordin – volume: 176 start-page: 242 year: 2002 end-page: 243 ident: bb0320 article-title: Vitamin D deficiency and multicultural Australia publication-title: MJA contributor: fullname: Glendenning – volume: 9 start-page: 394 year: 1999 end-page: 397 ident: bb0075 article-title: An international comparison of serum 25-hydroxyvitamin D measurements publication-title: Osteoporos Int contributor: fullname: Holick – volume: 26 start-page: 434 year: 2011 end-page: 436 ident: bb0280 article-title: Overestimation of the 25(OH)D serum concentration with the automated IDS EIA kit publication-title: J Bone Miner Res contributor: fullname: Souberbielle – volume: 168 start-page: 103 year: 2008 end-page: 108 ident: bb0115 article-title: Effects of ergocalciferol added to calcium on the risk of falls in elderly high-risk women publication-title: Arch Intern Med contributor: fullname: Zhu – volume: 51 start-page: 1683 year: 2005 end-page: 1690 ident: bb0365 article-title: Routine isotope-dilution liquid chromatography–tandem mass spectrometry assay for simultaneous measurement of the 25-hydroxy metabolites of vitamins D2 and D3 publication-title: Clin Chem contributor: fullname: Rainbow – volume: 1 start-page: 589 year: 1979 ident: bb0045 article-title: Plasma 25-hydroxy vitamin D concentrations in patients with fractures of the femoral neck publication-title: Br Med J contributor: fullname: Nordin – volume: 305 start-page: 453 year: 2011 end-page: 454 ident: bb0135 article-title: IOM endorses vitamin D, calcium only for bone health, dispels deficiency claims publication-title: JAMA contributor: fullname: Slomski – volume: 46 start-page: 1852 year: 2007 end-page: 1857 ident: bb0150 article-title: Effect of annual intramuscular vitamin D on fracture risk in elderly men and women—a population-based, randomized, double-blind, placebo-controlled trial publication-title: Rheumatology (Oxford) contributor: fullname: Cooper – volume: 128 start-page: 1414 year: 2011 end-page: 1424 ident: bb0230 article-title: Meta-analysis of observational studies of serum 25-hydroxyvitamin D levels and colorectal, breast and prostate cancer and colorectal adenoma publication-title: Int J Cancer contributor: fullname: Sneyd – volume: 149 start-page: 242 year: 2008 end-page: 250 ident: bb0110 article-title: Serum 25-hydroxyvitamin D concentrations and risk for hip fractures publication-title: Ann Intern Med contributor: fullname: Bauer – volume: 33 start-page: 992 year: 1971 end-page: 995 ident: bb0255 article-title: Competitive protein-binding radioassay for 25-hydroxycholecalciferol publication-title: J Clin Endocrinol Metab contributor: fullname: Chyu – volume: 51 start-page: 1533 year: 2003 end-page: 1538 ident: bb0160 article-title: Serum vitamin D and falls in older women in residential care in Australia publication-title: J Am Geriatr Soc contributor: fullname: Stein – volume: 339 start-page: b3692 year: 2009 ident: bb0120 article-title: Fall prevention with supplemental and active forms of vitamin D: a meta-analysis of randomised controlled trials publication-title: BMJ contributor: fullname: Theiler – volume: 33 start-page: 554 year: 1971 end-page: 557 ident: bb0260 article-title: Competitive binding assay for vitamin D and 25-OH vitamin D publication-title: J Clin Endocrinol Metab contributor: fullname: Potts – volume: 78 start-page: 112 year: 2000 end-page: 120 ident: bb0350 article-title: Natural metabolites of 1alpha,25-dihydroxyvitamin D(3) retain biologic activity mediated through the vitamin D receptor publication-title: J Cell Biochem contributor: fullname: Lindley – volume: 49 start-page: 159 year: 2012 end-page: 165 ident: bb0300 article-title: Evaluation of 25-hydroxyvitamin D assay on the immunodiagnostics systems iSYS analyser publication-title: Ann Clin Biochem contributor: fullname: O'Loughlin – volume: 21 start-page: 1151 year: 2010 end-page: 1154 ident: bb0130 article-title: IOF position statement: vitamin D recommendations for older adults publication-title: Osteoporos Int contributor: fullname: Fuleihan – volume: 172 start-page: 406 year: 2000 end-page: 407 ident: bb0220 article-title: Vitamin D insufficiency and hyperparathyroidism in Perth blood donors publication-title: MJA contributor: fullname: Flicker – volume: 45 start-page: 153 year: 2008 end-page: 159 ident: bb0380 article-title: Accuracy and clinical implications of seven 25-hydroxyvitamin D methods compared with liquid chromatography–tandem mass spectrometry as a reference publication-title: Ann Clin Biochem contributor: fullname: Niederau – volume: 31 start-page: 1815 year: 1985 end-page: 1819 ident: bb0275 article-title: Improved radioimmunoassay for vitamin D and its use in assessing vitamin D status publication-title: Clin Chem contributor: fullname: Napoli – volume: 25 start-page: 305 year: 2010 end-page: 312 ident: bb0055 article-title: Bone mineralization defects and vitamin D deficiency: histomorphometric analysis of iliac crest bone biopsies and circulating 25-hydroxyvitamin D in 675 patients publication-title: J Bone Miner Res contributor: fullname: Meier – volume: 85 start-page: 1586 year: 2007 end-page: 1591 ident: bb0250 article-title: Vitamin D and calcium supplementation reduces cancer risk: results of a randomized trial publication-title: Am J Clin Nutr contributor: fullname: Heaney – volume: 73 start-page: 277 year: 2010 end-page: 285 ident: bb0155 article-title: Reducing fracture risk with calcium and vitamin D publication-title: Clin Endocrinol (Oxf) contributor: fullname: Kuchuk – volume: 2 start-page: 84 year: 1974 end-page: 85 ident: bb0040 article-title: Seasonal variation of histological osteomalacia in femoral-neck fractures publication-title: Lancet contributor: fullname: Nordin – volume: 1 start-page: 229 year: 1974 end-page: 233 ident: bb0035 article-title: Frequency of osteomalacia and osteoporosis in fractures of the proximal femur publication-title: Lancet contributor: fullname: Nordin – volume: 362 start-page: 1389 year: 2003 end-page: 1400 ident: bb0030 publication-title: Lancet contributor: fullname: Rickets – volume: 183 start-page: 213 year: 2005 end-page: 214 ident: bb0210 article-title: Fit for a fracture publication-title: MJA contributor: fullname: Glendenning – volume: 48 start-page: 160 year: 2009 end-page: 166 ident: bb0085 article-title: Responses of parathyroid hormone to vitamin D supplementation: a systematic review of clinical trials publication-title: Arch Gerontol Geriatr contributor: fullname: Tilvis – volume: 22 start-page: 142 year: 2003 end-page: 146 ident: bb0060 article-title: Calcium absorption varies within the reference range for serum 25-hydroxyvitamin D publication-title: J Am Coll Nutr contributor: fullname: Bendich – volume: 9 start-page: 709 year: 2010 end-page: 715 ident: bb0235 article-title: Vitamin D and musculoskeletal health, cardiovascular disease, autoimmunity and cancer: recommendations for clinical practice publication-title: Autoimmun Rev contributor: fullname: Wang – volume: 80 start-page: 298 year: 1977 end-page: 305 ident: bb0265 article-title: Determination of 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3 in human plasma using high-pressure liquid chromatography publication-title: Anal Biochem contributor: fullname: DeLuca – volume: 96 start-page: 1320 year: 2011 end-page: 1326 ident: bb0185 article-title: Vitamin d and hyperparathyroidism in obesity publication-title: J Clin Endocrinol Metab contributor: fullname: Diaz – volume: 116 start-page: 634 year: 2004 end-page: 639 ident: bb0100 article-title: Positive association between 25-hydroxy vitamin D levels and bone mineral density: a population-based study of younger and older adults publication-title: Am J Med contributor: fullname: Dawson-Hughes – volume: 27 start-page: 170 year: 2011 end-page: 176 ident: bb0140 article-title: Effects of three monthly oral 150,000 IU cholecalciferol supplementation on falls, mobility and muscle strength in older postmenopausal women: a randomised controlled trial publication-title: J Bone Miner Res contributor: fullname: Prince – volume: 291 start-page: 1999 year: 2004 end-page: 2006 ident: bb0020 article-title: Effect of vitamin D on falls: a meta-analysis publication-title: JAMA contributor: fullname: Zee – volume: 364 start-page: 1385 year: 2011 end-page: 1387 ident: bb0240 article-title: Vitamin D and prevention of cancer—ready for prime time? publication-title: N Engl J Med contributor: fullname: Clinton – volume: 250 start-page: 361 year: 2001 end-page: 366 ident: bb0190 article-title: Prevalence of undiagnosed coeliac syndrome in osteoporotic women publication-title: J Intern Med contributor: fullname: Avanzati – volume: 73 start-page: 299 year: 2010 end-page: 304 ident: bb0200 article-title: Association between 25-hydroxyvitamin D, somatic muscle weakness and falls risk in end-stage renal failure publication-title: Clin Endocrinol (Oxf) contributor: fullname: Glendenning – volume: 177 start-page: 280 year: 2002 ident: bb0205 article-title: Low rate of compliance with ergocalciferol therapy in vitamin-D-deficient patients with hip fracture publication-title: MJA contributor: fullname: Glendenning – volume: 46 start-page: 79 year: 2009 end-page: 81 ident: bb0375 article-title: Use of a common standard improves the performance of liquid chromatography–tandem mass spectrometry methods for serum 25-hydroxyvitamin-D publication-title: Ann Clin Biochem contributor: fullname: Jones – volume: 175 start-page: 251 year: 2001 end-page: 252 ident: bb0170 article-title: Vitamin D deficiency in veiled or dark-skinned pregnant women publication-title: MJA contributor: fullname: Morley – volume: 338 start-page: 777 year: 1998 end-page: 783 ident: bb0195 article-title: Hypovitaminosis D in medical inpatients publication-title: N Engl J Med contributor: fullname: Kitch – volume: 49 start-page: 253 year: 2011 end-page: 256 ident: bb0360 article-title: Full-scan mass spectral evidence for 3-epi-25-hydroxyvitamin D in serum of infants and adults publication-title: Clin Chem Lab Med contributor: fullname: Thienpont – volume: 43 start-page: 23 year: 2006 end-page: 30 ident: bb0325 article-title: Current assays overestimate 25-hydroxyvitamin D3 and underestimate 25-hydroxyvitamin D2 compared with HPLC: need for assay-specific decision limits and metabolite-specific assays publication-title: Ann Clin Biochem contributor: fullname: Goldswain – volume: 49 start-page: 555 year: 2011 end-page: 558 ident: bb0315 article-title: Cross-reactivity of 25-hydroxy vitamin D2 from different commercial immunoassays for 25-hydroxy vitamin D: an evaluation without spiked samples publication-title: Clin Chem Lab Med contributor: fullname: Souberbielle – volume: 94 start-page: 1244 year: 2009 end-page: 1250 ident: bb0090 article-title: Relationships of serum 25-hydroxyvitamin D to bone mineral density and serum parathyroid hormone and markers of bone turnover in older persons publication-title: J Clin Endocrinol Metab contributor: fullname: Lips – volume: 303 start-page: 1815 year: 2010 end-page: 1822 ident: bb0145 article-title: Annual high-dose oral vitamin D and falls and fractures in older women: a randomized controlled trial publication-title: JAMA contributor: fullname: Young – volume: 24 start-page: 287 year: 1978 end-page: 298 ident: bb0270 article-title: Assay of vitamins D2 and D3, and 25-hydroxyvitamins D2 and D3 in human plasma by high-performance liquid chromatography publication-title: Clin Chem contributor: fullname: Jones – volume: 40 start-page: 546 year: 2003 end-page: 551 ident: bb0295 article-title: Issues of methodology, standardization and metabolite recognition for 25-hydroxyvitamin D when comparing the DiaSorin radioimmunoassay and the Nichols Advantage automated chemiluminescence protein-binding assay in hip fracture cases publication-title: Ann Clin Biochem contributor: fullname: Goldswain – volume: 43 start-page: 368 year: 2011 end-page: 371 ident: bb0305 article-title: Overreporting of vitamin D deficiency with the Roche Elecsys Vitamin D3 (25-OH) method publication-title: Pathology contributor: fullname: Schneider – volume: 329 start-page: 228 year: 1996 end-page: 234 ident: bb0355 article-title: 1 alpha,25-(OH)2-vitamin D3 analogs with minimal in vivo calcemic activity can stimulate significant transepithelial calcium transport and mRNA expression in vitro publication-title: Arch Biochem Biophys contributor: fullname: Wood – volume: 45 start-page: 870 year: 2009 end-page: 875 ident: bb0330 article-title: Serum 25-hydroxyvitamin D levels in vitamin D-insufficient hip fracture patients after supplementation with ergocalciferol and cholecalciferol publication-title: Bone contributor: fullname: Inderjeeth – volume: 33 start-page: 598 year: 2003 end-page: 603 ident: bb0215 article-title: Diagnosis of primary hyperparathyroidism: controversies, practical issues and the need for Australian guidelines publication-title: Intern Med J contributor: fullname: Glendenning – volume: 23 start-page: 1052 year: 2008 end-page: 1060 ident: bb0065 article-title: Vitamin D insufficiency: disease or no disease? publication-title: J Bone Miner Res contributor: fullname: Shafer – volume: 96 start-page: 1911 year: 2011 end-page: 1930 ident: bb0125 article-title: Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline publication-title: J Clin Endocrinol Metab contributor: fullname: Heaney – volume: 94 start-page: 2773 year: 2009 end-page: 2780 ident: bb0105 article-title: Serum 25-hydroxyvitamin D levels and rate of hip bone loss in older men publication-title: J Clin Endocrinol Metab contributor: fullname: Cummings – volume: 327 start-page: 1637 year: 1992 end-page: 1642 ident: bb0005 article-title: Vitamin D3 and calcium to prevent hip fractures in the elderly women publication-title: N Engl J Med contributor: fullname: Arnaud – volume: 337 start-page: 670 year: 1997 end-page: 676 ident: bb0010 article-title: Effect of calcium and vitamin D supplementation on bone density in men and women 65 publication-title: N Engl J Med contributor: fullname: Dallal – volume: 47 start-page: 357 year: 2001 end-page: 365 ident: bb0290 article-title: Validation of the first automated chemiluminescence protein-binding assay for the detection of 25-hydroxycalciferol publication-title: Clin Lab contributor: fullname: Schmidt – volume: 57 start-page: 441 year: 2011 end-page: 448 ident: bb0335 article-title: Candidate reference measurement procedures for serum 25-hydroxyvitamin D3 and 25-hydroxyvitamin D2 by using isotope-dilution liquid chromatography–tandem mass spectrometry publication-title: Clin Chem contributor: fullname: Thienpont – volume: 190 start-page: 102 year: 2009 ident: bb0180 article-title: Vitamin D deficiency in Sydney skin cancer patients publication-title: MJA contributor: fullname: Damian – volume: 120 start-page: U2730 year: 2007 ident: bb0015 article-title: Vitamin D and muscle strength in patients with previous fractures publication-title: N Z Med J contributor: fullname: Tapper – volume: 22 start-page: 1668 year: 2007 end-page: 1671 ident: bb0025 article-title: Relative value of 25(OH)D and 1,25(OH)2D measurements publication-title: J Bone Miner Res contributor: fullname: Lips – volume: 350 start-page: 991 year: 2004 end-page: 1004 ident: bb0245 article-title: Estrogen plus progestin and colorectal cancer in postmenopausal women publication-title: N Engl J Med contributor: fullname: Rodabough – volume: 65 start-page: 1005 year: 2011 end-page: 1015 ident: bb0225 article-title: Vitamin D and type 2 diabetes: a systematic review publication-title: Eur J Clin Nutr contributor: fullname: Pittas – volume: 50 start-page: 2195 year: 2004 end-page: 2197 ident: bb0310 article-title: How accurate are assays for 25-hydroxyvitamin D? Data from the international vitamin D external quality assessment scheme publication-title: Clin Chem contributor: fullname: Berry – volume: 49 start-page: 253 year: 2011 ident: 10.1016/j.clinbiochem.2012.04.002_bb0360 article-title: Full-scan mass spectral evidence for 3-epi-25-hydroxyvitamin D in serum of infants and adults publication-title: Clin Chem Lab Med doi: 10.1515/CCLM.2011.050 contributor: fullname: Stepman – volume: 45 start-page: 153 year: 2008 ident: 10.1016/j.clinbiochem.2012.04.002_bb0380 article-title: Accuracy and clinical implications of seven 25-hydroxyvitamin D methods compared with liquid chromatography–tandem mass spectrometry as a reference publication-title: Ann Clin Biochem doi: 10.1258/acb.2007.007091 contributor: fullname: Roth – volume: 362 start-page: 1389 year: 2003 ident: 10.1016/j.clinbiochem.2012.04.002_bb0030 publication-title: Lancet doi: 10.1016/S0140-6736(03)14636-3 contributor: fullname: Wharton – volume: 33 start-page: 554 year: 1971 ident: 10.1016/j.clinbiochem.2012.04.002_bb0260 article-title: Competitive binding assay for vitamin D and 25-OH vitamin D publication-title: J Clin Endocrinol Metab doi: 10.1210/jcem-33-3-554 contributor: fullname: Belsey – volume: 91 start-page: 3055 year: 2006 ident: 10.1016/j.clinbiochem.2012.04.002_bb0345 article-title: C-3 epimers can account for a significant proportion of total circulating 25-hydroxyvitamin D in infants, complicating accurate measurement and interpretation of vitamin D status publication-title: J Clin Endocrinol Metab doi: 10.1210/jc.2006-0710 contributor: fullname: Singh – volume: 49 start-page: 555 year: 2011 ident: 10.1016/j.clinbiochem.2012.04.002_bb0315 article-title: Cross-reactivity of 25-hydroxy vitamin D2 from different commercial immunoassays for 25-hydroxy vitamin D: an evaluation without spiked samples publication-title: Clin Chem Lab Med doi: 10.1515/CCLM.2011.072 contributor: fullname: Cavalier – volume: 338 start-page: 777 year: 1998 ident: 10.1016/j.clinbiochem.2012.04.002_bb0195 article-title: Hypovitaminosis D in medical inpatients publication-title: N Engl J Med doi: 10.1056/NEJM199803193381201 contributor: fullname: Thomas – volume: 172 start-page: 406 year: 2000 ident: 10.1016/j.clinbiochem.2012.04.002_bb0220 article-title: Vitamin D insufficiency and hyperparathyroidism in Perth blood donors publication-title: MJA contributor: fullname: Vasikaran – volume: 329 start-page: 228 year: 1996 ident: 10.1016/j.clinbiochem.2012.04.002_bb0355 article-title: 1 alpha,25-(OH)2-vitamin D3 analogs with minimal in vivo calcemic activity can stimulate significant transepithelial calcium transport and mRNA expression in vitro publication-title: Arch Biochem Biophys doi: 10.1006/abbi.1996.0213 contributor: fullname: Fleet – volume: 73 start-page: 277 year: 2010 ident: 10.1016/j.clinbiochem.2012.04.002_bb0155 article-title: Reducing fracture risk with calcium and vitamin D publication-title: Clin Endocrinol (Oxf) doi: 10.1111/j.1365-2265.2009.03701.x contributor: fullname: Lips – volume: 175 start-page: 251 year: 2001 ident: 10.1016/j.clinbiochem.2012.04.002_bb0170 article-title: Vitamin D deficiency in veiled or dark-skinned pregnant women publication-title: MJA contributor: fullname: Grover – volume: 9 start-page: 709 year: 2010 ident: 10.1016/j.clinbiochem.2012.04.002_bb0235 article-title: Vitamin D and musculoskeletal health, cardiovascular disease, autoimmunity and cancer: recommendations for clinical practice publication-title: Autoimmun Rev doi: 10.1016/j.autrev.2010.06.009 contributor: fullname: Souberbielle – volume: 116 start-page: 634 year: 2004 ident: 10.1016/j.clinbiochem.2012.04.002_bb0100 article-title: Positive association between 25-hydroxy vitamin D levels and bone mineral density: a population-based study of younger and older adults publication-title: Am J Med doi: 10.1016/j.amjmed.2003.12.029 contributor: fullname: Bischoff-Ferrari – volume: 94 start-page: 1244 year: 2009 ident: 10.1016/j.clinbiochem.2012.04.002_bb0090 article-title: Relationships of serum 25-hydroxyvitamin D to bone mineral density and serum parathyroid hormone and markers of bone turnover in older persons publication-title: J Clin Endocrinol Metab doi: 10.1210/jc.2008-1832 contributor: fullname: Kuchuk – volume: 22 start-page: 477 year: 2001 ident: 10.1016/j.clinbiochem.2012.04.002_bb0050 article-title: Vitamin D deficiency and secondary hyperparathyroidism in the elderly: consequences for bone loss and fractures and therapeutic implications publication-title: Endocr Rev doi: 10.1210/er.22.4.477 contributor: fullname: Lips – volume: 51 start-page: 1683 year: 2005 ident: 10.1016/j.clinbiochem.2012.04.002_bb0365 article-title: Routine isotope-dilution liquid chromatography–tandem mass spectrometry assay for simultaneous measurement of the 25-hydroxy metabolites of vitamins D2 and D3 publication-title: Clin Chem doi: 10.1373/clinchem.2005.052936 contributor: fullname: Maunsell – volume: 337 start-page: 670 year: 1997 ident: 10.1016/j.clinbiochem.2012.04.002_bb0010 article-title: Effect of calcium and vitamin D supplementation on bone density in men and women 65years of age or older publication-title: N Engl J Med doi: 10.1056/NEJM199709043371003 contributor: fullname: Dawson-Hughes – volume: 339 start-page: b3692 year: 2009 ident: 10.1016/j.clinbiochem.2012.04.002_bb0120 article-title: Fall prevention with supplemental and active forms of vitamin D: a meta-analysis of randomised controlled trials publication-title: BMJ doi: 10.1136/bmj.b3692 contributor: fullname: Bischoff-Ferrari – volume: 46 start-page: 79 year: 2009 ident: 10.1016/j.clinbiochem.2012.04.002_bb0375 article-title: Use of a common standard improves the performance of liquid chromatography–tandem mass spectrometry methods for serum 25-hydroxyvitamin-D publication-title: Ann Clin Biochem doi: 10.1258/acb.2008.008135 contributor: fullname: Carter – volume: 26 start-page: 434 year: 2011 ident: 10.1016/j.clinbiochem.2012.04.002_bb0280 article-title: Overestimation of the 25(OH)D serum concentration with the automated IDS EIA kit publication-title: J Bone Miner Res doi: 10.1002/jbmr.190 contributor: fullname: Cavalier – volume: 120 start-page: U2730 year: 2007 ident: 10.1016/j.clinbiochem.2012.04.002_bb0015 article-title: Vitamin D and muscle strength in patients with previous fractures publication-title: N Z Med J contributor: fullname: Inderjeeth – volume: 45 start-page: 870 year: 2009 ident: 10.1016/j.clinbiochem.2012.04.002_bb0330 article-title: Serum 25-hydroxyvitamin D levels in vitamin D-insufficient hip fracture patients after supplementation with ergocalciferol and cholecalciferol publication-title: Bone doi: 10.1016/j.bone.2009.07.015 contributor: fullname: Glendenning – volume: 176 start-page: 560 year: 2002 ident: 10.1016/j.clinbiochem.2012.04.002_bb0165 article-title: Vitamin D deficiency is common in frail institutionalised older people in northern Sydney publication-title: MJA contributor: fullname: Sambrook – volume: 183 start-page: 213 year: 2005 ident: 10.1016/j.clinbiochem.2012.04.002_bb0210 article-title: Fit for a fracture publication-title: MJA contributor: fullname: Seymour – volume: 291 start-page: 1999 year: 2004 ident: 10.1016/j.clinbiochem.2012.04.002_bb0020 article-title: Effect of vitamin D on falls: a meta-analysis publication-title: JAMA doi: 10.1001/jama.291.16.1999 contributor: fullname: Bischoff-Ferrari – volume: 40 start-page: 546 year: 2003 ident: 10.1016/j.clinbiochem.2012.04.002_bb0295 article-title: Issues of methodology, standardization and metabolite recognition for 25-hydroxyvitamin D when comparing the DiaSorin radioimmunoassay and the Nichols Advantage automated chemiluminescence protein-binding assay in hip fracture cases publication-title: Ann Clin Biochem doi: 10.1258/000456303322326470 contributor: fullname: Glendenning – volume: 128 start-page: 1414 year: 2011 ident: 10.1016/j.clinbiochem.2012.04.002_bb0230 article-title: Meta-analysis of observational studies of serum 25-hydroxyvitamin D levels and colorectal, breast and prostate cancer and colorectal adenoma publication-title: Int J Cancer doi: 10.1002/ijc.25439 contributor: fullname: Gandini – volume: 46 start-page: 1852 year: 2007 ident: 10.1016/j.clinbiochem.2012.04.002_bb0150 article-title: Effect of annual intramuscular vitamin D on fracture risk in elderly men and women—a population-based, randomized, double-blind, placebo-controlled trial publication-title: Rheumatology (Oxford) doi: 10.1093/rheumatology/kem240 contributor: fullname: Smith – volume: 89 start-page: 139 year: 2007 ident: 10.1016/j.clinbiochem.2012.04.002_bb0175 article-title: Does a high UV environment ensure adequate vitamin D status? publication-title: J Photochem Photobiol B doi: 10.1016/j.jphotobiol.2007.09.008 contributor: fullname: Kimlin – volume: 33 start-page: 992 year: 1971 ident: 10.1016/j.clinbiochem.2012.04.002_bb0255 article-title: Competitive protein-binding radioassay for 25-hydroxycholecalciferol publication-title: J Clin Endocrinol Metab doi: 10.1210/jcem-33-6-992 contributor: fullname: Haddad – volume: 305 start-page: 453 year: 2011 ident: 10.1016/j.clinbiochem.2012.04.002_bb0135 article-title: IOM endorses vitamin D, calcium only for bone health, dispels deficiency claims publication-title: JAMA doi: 10.1001/jama.2011.50 contributor: fullname: Slomski – volume: 22 start-page: 142 year: 2003 ident: 10.1016/j.clinbiochem.2012.04.002_bb0060 article-title: Calcium absorption varies within the reference range for serum 25-hydroxyvitamin D publication-title: J Am Coll Nutr doi: 10.1080/07315724.2003.10719287 contributor: fullname: Heaney – volume: 9 start-page: 394 year: 1999 ident: 10.1016/j.clinbiochem.2012.04.002_bb0075 article-title: An international comparison of serum 25-hydroxyvitamin D measurements publication-title: Osteoporos Int doi: 10.1007/s001980050162 contributor: fullname: Lips – volume: 303 start-page: 1815 year: 2010 ident: 10.1016/j.clinbiochem.2012.04.002_bb0145 article-title: Annual high-dose oral vitamin D and falls and fractures in older women: a randomized controlled trial publication-title: JAMA doi: 10.1001/jama.2010.594 contributor: fullname: Sanders – volume: 27 start-page: 170 year: 2011 ident: 10.1016/j.clinbiochem.2012.04.002_bb0140 article-title: Effects of three monthly oral 150,000 IU cholecalciferol supplementation on falls, mobility and muscle strength in older postmenopausal women: a randomised controlled trial publication-title: J Bone Miner Res doi: 10.1002/jbmr.524 contributor: fullname: Glendenning – volume: 168 start-page: 103 year: 2008 ident: 10.1016/j.clinbiochem.2012.04.002_bb0115 article-title: Effects of ergocalciferol added to calcium on the risk of falls in elderly high-risk women publication-title: Arch Intern Med doi: 10.1001/archinternmed.2007.31 contributor: fullname: Prince – volume: 279 start-page: 15897 year: 2004 ident: 10.1016/j.clinbiochem.2012.04.002_bb0340 article-title: C-3 epimerization of vitamin D3 metabolites and further metabolism of C-3 epimers: 25-hydroxyvitamin D3 is metabolized to 3-epi-25-hydroxyvitamin D3 and subsequently metabolized through C-1alpha or C-24 hydroxylation publication-title: J Biol Chem doi: 10.1074/jbc.M311473200 contributor: fullname: Kamao – volume: 96 start-page: 1911 year: 2011 ident: 10.1016/j.clinbiochem.2012.04.002_bb0125 article-title: Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline publication-title: J Clin Endocrinol Metab doi: 10.1210/jc.2011-0385 contributor: fullname: Holick – volume: 73 start-page: 299 year: 2010 ident: 10.1016/j.clinbiochem.2012.04.002_bb0200 article-title: Association between 25-hydroxyvitamin D, somatic muscle weakness and falls risk in end-stage renal failure publication-title: Clin Endocrinol (Oxf) doi: 10.1111/j.1365-2265.2010.03821.x contributor: fullname: Boudville – volume: 250 start-page: 361 year: 2001 ident: 10.1016/j.clinbiochem.2012.04.002_bb0190 article-title: Prevalence of undiagnosed coeliac syndrome in osteoporotic women publication-title: J Intern Med doi: 10.1046/j.1365-2796.2001.00895.x contributor: fullname: Nuti – volume: 149 start-page: 242 year: 2008 ident: 10.1016/j.clinbiochem.2012.04.002_bb0110 article-title: Serum 25-hydroxyvitamin D concentrations and risk for hip fractures publication-title: Ann Intern Med doi: 10.7326/0003-4819-149-4-200808190-00005 contributor: fullname: Cauley – volume: 51 start-page: 1533 year: 2003 ident: 10.1016/j.clinbiochem.2012.04.002_bb0160 article-title: Serum vitamin D and falls in older women in residential care in Australia publication-title: J Am Geriatr Soc doi: 10.1046/j.1532-5415.2003.51510.x contributor: fullname: Flicker – volume: 50 start-page: 2195 year: 2004 ident: 10.1016/j.clinbiochem.2012.04.002_bb0310 article-title: How accurate are assays for 25-hydroxyvitamin D? Data from the international vitamin D external quality assessment scheme publication-title: Clin Chem doi: 10.1373/clinchem.2004.040683 contributor: fullname: Carter – volume: 43 start-page: 23 year: 2006 ident: 10.1016/j.clinbiochem.2012.04.002_bb0325 article-title: Current assays overestimate 25-hydroxyvitamin D3 and underestimate 25-hydroxyvitamin D2 compared with HPLC: need for assay-specific decision limits and metabolite-specific assays publication-title: Ann Clin Biochem doi: 10.1258/000456306775141650 contributor: fullname: Glendenning – volume: 23 start-page: 1052 year: 2008 ident: 10.1016/j.clinbiochem.2012.04.002_bb0065 article-title: Vitamin D insufficiency: disease or no disease? publication-title: J Bone Miner Res doi: 10.1359/jbmr.080230 contributor: fullname: Hansen – volume: 47 start-page: 357 year: 2001 ident: 10.1016/j.clinbiochem.2012.04.002_bb0290 article-title: Validation of the first automated chemiluminescence protein-binding assay for the detection of 25-hydroxycalciferol publication-title: Clin Lab contributor: fullname: Roth – volume: 78 start-page: 112 year: 2000 ident: 10.1016/j.clinbiochem.2012.04.002_bb0350 article-title: Natural metabolites of 1alpha,25-dihydroxyvitamin D(3) retain biologic activity mediated through the vitamin D receptor publication-title: J Cell Biochem doi: 10.1002/(SICI)1097-4644(20000701)78:1<112::AID-JCB10>3.0.CO;2-7 contributor: fullname: Harant – volume: 48 start-page: 160 year: 2009 ident: 10.1016/j.clinbiochem.2012.04.002_bb0085 article-title: Responses of parathyroid hormone to vitamin D supplementation: a systematic review of clinical trials publication-title: Arch Gerontol Geriatr doi: 10.1016/j.archger.2007.12.005 contributor: fullname: Bjorkman – volume: 57 start-page: 441 year: 2011 ident: 10.1016/j.clinbiochem.2012.04.002_bb0335 article-title: Candidate reference measurement procedures for serum 25-hydroxyvitamin D3 and 25-hydroxyvitamin D2 by using isotope-dilution liquid chromatography–tandem mass spectrometry publication-title: Clin Chem doi: 10.1373/clinchem.2010.152553 contributor: fullname: Stepman – volume: 33 start-page: 598 year: 2003 ident: 10.1016/j.clinbiochem.2012.04.002_bb0215 article-title: Diagnosis of primary hyperparathyroidism: controversies, practical issues and the need for Australian guidelines publication-title: Intern Med J doi: 10.1111/j.1445-5994.2003.00484.x contributor: fullname: Glendenning – volume: 80 start-page: 298 year: 1977 ident: 10.1016/j.clinbiochem.2012.04.002_bb0265 article-title: Determination of 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3 in human plasma using high-pressure liquid chromatography publication-title: Anal Biochem doi: 10.1016/0003-2697(77)90648-0 contributor: fullname: Eisman – volume: 1 start-page: 229 year: 1974 ident: 10.1016/j.clinbiochem.2012.04.002_bb0035 article-title: Frequency of osteomalacia and osteoporosis in fractures of the proximal femur publication-title: Lancet doi: 10.1016/S0140-6736(74)92545-8 contributor: fullname: Aaron – volume: 85 start-page: 1586 year: 2007 ident: 10.1016/j.clinbiochem.2012.04.002_bb0250 article-title: Vitamin D and calcium supplementation reduces cancer risk: results of a randomized trial publication-title: Am J Clin Nutr doi: 10.1093/ajcn/85.6.1586 contributor: fullname: Lappe – volume: 294 start-page: 2336 year: 2005 ident: 10.1016/j.clinbiochem.2012.04.002_bb0080 article-title: Relationship between serum parathyroid hormone levels, vitamin D sufficiency, and calcium intake publication-title: JAMA doi: 10.1001/jama.294.18.2336 contributor: fullname: Steingrimsdottir – volume: 190 start-page: 102 year: 2009 ident: 10.1016/j.clinbiochem.2012.04.002_bb0180 article-title: Vitamin D deficiency in Sydney skin cancer patients publication-title: MJA contributor: fullname: McCombie – volume: 77 start-page: 522 year: 2003 ident: 10.1016/j.clinbiochem.2012.04.002_bb0285 article-title: Issues of standardization and assay-specific clinical decision limits for the measurement of 25-hydroxyvitamin D publication-title: Am J Clin Nutr doi: 10.1093/ajcn/77.2.522 contributor: fullname: Glendenning – volume: 350 start-page: 991 year: 2004 ident: 10.1016/j.clinbiochem.2012.04.002_bb0245 article-title: Estrogen plus progestin and colorectal cancer in postmenopausal women publication-title: N Engl J Med doi: 10.1056/NEJMoa032071 contributor: fullname: Chlebowski – volume: 25 start-page: 305 year: 2010 ident: 10.1016/j.clinbiochem.2012.04.002_bb0055 article-title: Bone mineralization defects and vitamin D deficiency: histomorphometric analysis of iliac crest bone biopsies and circulating 25-hydroxyvitamin D in 675 patients publication-title: J Bone Miner Res doi: 10.1359/jbmr.090728 contributor: fullname: Priemel – volume: 96 start-page: 1320 year: 2011 ident: 10.1016/j.clinbiochem.2012.04.002_bb0185 article-title: Vitamin d and hyperparathyroidism in obesity publication-title: J Clin Endocrinol Metab doi: 10.1210/jc.2010-2202 contributor: fullname: Grethen – volume: 327 start-page: 1637 year: 1992 ident: 10.1016/j.clinbiochem.2012.04.002_bb0005 article-title: Vitamin D3 and calcium to prevent hip fractures in the elderly women publication-title: N Engl J Med doi: 10.1056/NEJM199212033272305 contributor: fullname: Chapuy – volume: 21 start-page: 1151 year: 2010 ident: 10.1016/j.clinbiochem.2012.04.002_bb0130 article-title: IOF position statement: vitamin D recommendations for older adults publication-title: Osteoporos Int doi: 10.1007/s00198-010-1285-3 contributor: fullname: Dawson-Hughes – volume: 10 start-page: 46 year: 2011 ident: 10.1016/j.clinbiochem.2012.04.002_bb0370 article-title: Misleading measures in Vitamin D analysis: a novel LC–MS/MS assay to account for epimers and isobars publication-title: Nutr J doi: 10.1186/1475-2891-10-46 contributor: fullname: Shah – volume: 24 start-page: 287 year: 1978 ident: 10.1016/j.clinbiochem.2012.04.002_bb0270 article-title: Assay of vitamins D2 and D3, and 25-hydroxyvitamins D2 and D3 in human plasma by high-performance liquid chromatography publication-title: Clin Chem doi: 10.1093/clinchem/24.2.287 contributor: fullname: Jones – volume: 22 start-page: 1668 year: 2007 ident: 10.1016/j.clinbiochem.2012.04.002_bb0025 article-title: Relative value of 25(OH)D and 1,25(OH)2D measurements publication-title: J Bone Miner Res doi: 10.1359/jbmr.070716 contributor: fullname: Lips – volume: 31 start-page: 626 year: 2002 ident: 10.1016/j.clinbiochem.2012.04.002_bb0095 article-title: Relationship between serum 25-hydroxyvitamin D and bone resorption markers in vitamin D insufficiency publication-title: Bone doi: 10.1016/S8756-3282(02)00866-9 contributor: fullname: Jesudason – volume: 364 start-page: 1385 year: 2011 ident: 10.1016/j.clinbiochem.2012.04.002_bb0240 article-title: Vitamin D and prevention of cancer—ready for prime time? publication-title: N Engl J Med doi: 10.1056/NEJMp1102022 contributor: fullname: Manson – volume: 2 start-page: 84 year: 1974 ident: 10.1016/j.clinbiochem.2012.04.002_bb0040 article-title: Seasonal variation of histological osteomalacia in femoral-neck fractures publication-title: Lancet doi: 10.1016/S0140-6736(74)91640-7 contributor: fullname: Aaron – volume: 65 start-page: 1005 year: 2011 ident: 10.1016/j.clinbiochem.2012.04.002_bb0225 article-title: Vitamin D and type 2 diabetes: a systematic review publication-title: Eur J Clin Nutr doi: 10.1038/ejcn.2011.118 contributor: fullname: Mitri – volume: 1 start-page: 589 year: 1979 ident: 10.1016/j.clinbiochem.2012.04.002_bb0045 article-title: Plasma 25-hydroxy vitamin D concentrations in patients with fractures of the femoral neck publication-title: Br Med J doi: 10.1136/bmj.1.6163.589 contributor: fullname: Baker – volume: 177 start-page: 280 year: 2002 ident: 10.1016/j.clinbiochem.2012.04.002_bb0205 article-title: Low rate of compliance with ergocalciferol therapy in vitamin-D-deficient patients with hip fracture publication-title: MJA contributor: fullname: Noble – volume: 31 start-page: 1815 year: 1985 ident: 10.1016/j.clinbiochem.2012.04.002_bb0275 article-title: Improved radioimmunoassay for vitamin D and its use in assessing vitamin D status publication-title: Clin Chem doi: 10.1093/clinchem/31.11.1815 contributor: fullname: Hollis – volume: 351 start-page: 805 year: 1998 ident: 10.1016/j.clinbiochem.2012.04.002_bb0070 article-title: Redefining vitamin D insufficiency publication-title: Lancet doi: 10.1016/S0140-6736(05)78933-9 contributor: fullname: Malabanan – volume: 176 start-page: 242 year: 2002 ident: 10.1016/j.clinbiochem.2012.04.002_bb0320 article-title: Vitamin D deficiency and multicultural Australia publication-title: MJA contributor: fullname: Glendenning – volume: 94 start-page: 2773 year: 2009 ident: 10.1016/j.clinbiochem.2012.04.002_bb0105 article-title: Serum 25-hydroxyvitamin D levels and rate of hip bone loss in older men publication-title: J Clin Endocrinol Metab doi: 10.1210/jc.2008-2786 contributor: fullname: Ensrud – volume: 43 start-page: 368 year: 2011 ident: 10.1016/j.clinbiochem.2012.04.002_bb0305 article-title: Overreporting of vitamin D deficiency with the Roche Elecsys Vitamin D3 (25-OH) method publication-title: Pathology doi: 10.1097/PAT.0b013e328346431c contributor: fullname: Connell – volume: 49 start-page: 159 year: 2012 ident: 10.1016/j.clinbiochem.2012.04.002_bb0300 article-title: Evaluation of 25-hydroxyvitamin D assay on the immunodiagnostics systems iSYS analyser publication-title: Ann Clin Biochem doi: 10.1258/acb.2011.011018 contributor: fullname: Cluse |
| SSID | ssj0002486 |
| Score | 2.1627178 |
| SecondaryResourceType | review_article |
| Snippet | Interest in vitamin D has intensified with the association of vitamin D deficiency (VDD) with many diseases. This review will outline the limitations of... |
| SourceID | proquest crossref pubmed elsevier |
| SourceType | Aggregation Database Index Database Publisher |
| StartPage | 901 |
| SubjectTerms | 25OHD target of treatment Animals Biomarkers - blood Biomarkers - urine Blood Chemical Analysis - standards Bone Density Calcifediol - blood Calcifediol - therapeutic use Dietary Supplements Humans Methods of 25OHD analysis Reference Standards Reference Values Vitamin D Vitamin D Deficiency - blood Vitamin D Deficiency - diagnosis Vitamin D Deficiency - drug therapy Vitamins - blood Vitamins - therapeutic use |
| Title | Vitamin D: Methods of 25 hydroxyvitamin D analysis, targeting at risk populations and selecting thresholds of treatment |
| URI | https://dx.doi.org/10.1016/j.clinbiochem.2012.04.002 https://www.ncbi.nlm.nih.gov/pubmed/22522083 https://search.proquest.com/docview/1026687976 |
| Volume | 45 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1LS-wwFD7oCF434uvq-CKCS6vTJNNWcSOjMl4ZVyruQtIm3F6wM9iquPG3e05fV0FBcNemSVt60nO-JN_JB7DrW-sCJ7jXM0Z60vX6nrFaer4Rhgc2kULThP7oKhjeyD93_bspGDS5MESrrH1_5dNLb12XHNRf82CSppTji-jG55T9ibglEtMwg-GIRx2YObm4HF61DpnLUvCR6nvUYBZ2_tO8KAHRpKRORXnpNDMo20mWT8LUVzC0DEfnCzBf40h2Ur3qIkzZbAl-DRr5tiWYHdWr5svwfJsW-j7N2OkRG5WK0TkbO8b77O9LQjSWp-Y60_UeJXusoohjYGO6YERAZ5NW6yvHegnLSwkdqlFgh8hpHau8b8tdX4Gb87PrwdCrBRe8WIRh4WGoj3lsjG9CG1uB2MQGjpNILvrTBId-Ig79Q6fpwNhECxdH2iW-NIaGHr74DZ1snNk1YAnnh0ZrEepAS4N_PXdxEFmRIGZwWNoF3nxfNan21VAN4eyfemcURUZRPanQKF04biyhPnQShf7_O813GuspNAatjOjMjh9zbIc4JQoRmnVhtTJr-1bo8DhHoLr-s4dvwBydVdzBTegUD492C_FMYbZhev_V36577Rt0xPcF |
| link.rule.ids | 315,783,787,4509,24128,27936,27937,45597,45691 |
| linkProvider | Elsevier |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1bT9swFD4CKgEviBUYhV2MxCMRje0mLdpL1Q216-UJJt4sO7FFJpFWJID495yT20Bi0qS9RY6dWD728Wf7O_4ATn1rXeAE97rGSE-6bs8zVkvPN8LwwMZSaNrQny-C8bX8edO7WYNRHQtDtMrK95c-vfDWVcp51ZrnqyShGF9ENz6n6E_ELX2xDi1EAwMcna3hZDpeNA6Zy0LwkfJ7VGATTv7QvCgA0SSkTkVx6bQzKJtNlnemqb_B0GI6utyFnQpHsmFZ1Q-wZtM2bI1q-bY2bM6rU_M9ePqV5PouSdn3CzYvFKMztnSM99jtc0w0lsf6PdPVHSVnrKSI48TGdM6IgM5WjdZXhvlilhUSOpQjxw6R0TlW8d2Gu74P15c_rkZjrxJc8CIRhrmHU33EI2N8E9rICsQmNnCcRHLRn8a49BNR6A-cpgdjYy1c1Ncu9qUxtPTwxQFspMvUHgKLOR8YrUWoAy0NjnruoqBvRYyYwWFqB3jdvmpV3quhasLZb_XKKIqMorpSoVE68K22hHrTSRT6_38pflJbT6Ex6GREp3b5kGE5xCn9EKFZBz6WZm1qhQ6PcwSqR__386-wNb6az9Rsspgewza9KXmEn2Ajv3-wnxHb5OZL1XdfAG5r-Pk |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Vitamin+D%3A+Methods+of+25+hydroxyvitamin+D+analysis%2C+targeting+at+risk+populations+and+selecting+thresholds+of+treatment&rft.jtitle=Clinical+biochemistry&rft.au=Glendenning%2C+Paul&rft.au=Inderjeeth%2C+Charles+A.&rft.date=2012-08-01&rft.pub=Elsevier+Inc&rft.issn=0009-9120&rft.eissn=1873-2933&rft.volume=45&rft.issue=12&rft.spage=901&rft.epage=906&rft_id=info:doi/10.1016%2Fj.clinbiochem.2012.04.002&rft.externalDocID=S0009912012001683 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0009-9120&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0009-9120&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0009-9120&client=summon |