In vitro application of drug-loaded hydrogel combined with 3D-printed porous scaffolds

• Published in: Biomedical materials (Bristol) Vol. 17; no. 6; pp. 65019 - 65035
• Main Authors: Huang, Haokun, Wu, Zhenhuan, Yang, Zhuofan, Fan, Xiaoxi, Bai, Siqi, Luo, Junsi, Chen, Minmin, Xie, Xiaoli
• Format: Journal Article
• Language: English
• Published: England IOP Publishing 01.11.2022
• Subjects: Alkaline Phosphatase; Alloys; Anti-Bacterial Agents - pharmacology; antibacterial effect; Chitosan; Hyaluronic Acid; Hydrogels; implant-associated infection; MRSA; Osteogenesis; Porosity; porous scaffolds; Printing, Three-Dimensional; Tissue Scaffolds - chemistry; Titanium - chemistry; Vancomycin - pharmacology; implant-associated infection; antibacterial effect; porous scaffolds; MRSA

Titanium mesh and three-dimensional titanium alloy scaffolds play a key role in addressing oral and maxillofacial bone defects, which can provide a specific environment and structure for bone growth and development. The two main causes of implant surgery failure are aseptic loosening and bacterial-i...