Croton antisyphiliticus Mart. attenuates the inflammatory response to carrageenan-induced pleurisy in mice

• Published in: Inflammopharmacology Vol. 22; no. 2; pp. 115 - 126
• Main Authors: dos Reis, Gustavo Oliveira, Vicente, Geison, de Carvalho, Francieli Kanumfre, Heller, Melina, Micke, Gustavo Amadeu, Pizzolatti, Moacir Geraldo, Fröde, Tânia Silvia
• Format: Journal Article
• Language: English
• Published: Basel Springer Basel 01.04.2014
• Subjects: Adenosine Deaminase - metabolism; Allergology; Animals; Anti-Inflammatory Agents - chemistry; Anti-Inflammatory Agents - pharmacology; Biomedical and Life Sciences; Biomedicine; Carrageenan - adverse effects; Croton; Croton - chemistry; Dermatology; Disease Models, Animal; Female; Gastroenterology; Immunology; Inflammation - drug therapy; Inflammation - metabolism; Interleukin-17 - metabolism; Leukocytes - drug effects; Leukocytes - metabolism; Mice; Nitrates - metabolism; Nitrites - metabolism; Peroxidase - metabolism; Pharmacology/Toxicology; Plant Extracts - chemistry; Plant Extracts - pharmacology; Pleurisy - chemically induced; Pleurisy - drug therapy; Pleurisy - metabolism; Research Article; Rheumatology; Tumor Necrosis Factor-alpha - metabolism; Pro-inflammatory cytokines; Anti-inflammatory effect; Quinic acid; Pro-inflammatory enzymes; Vitexin
• ISSN: 0925-4692; 1568-5608; 1568-5608
• DOI: 10.1007/s10787-013-0184-6

The aim of this study was to investigate the anti-inflammatory effect of the crude hydroalcoholic extract (CHE) from the aerial parts of Croton antisyphiliticus , its fractions and isolated compounds derived from it on the mouse model of pleurisy induced by carrageenan. The aerial parts of C. antisy...