Clinical significance of serum mitochondrial DNA in lung cancer

• Published in: Clinical biochemistry Vol. 46; no. 15; pp. 1474 - 1477
• Main Authors: Hou, Yu-Lei, Chen, Juan-Juan, Wu, Yan-Feng, Xue, Cheng-Jun, Li, Feng-Zeng, Zheng, Qian, Chen, Hui
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.10.2013
• Subjects: Adenocarcinoma - blood; Adenocarcinoma - diagnosis; Aged; Biomarkers, Tumor - blood; Carcinoma, Squamous Cell - blood; Carcinoma, Squamous Cell - diagnosis; Case-Control Studies; Diagnostic efficacy; DNA Copy Number Variations; DNA, Mitochondrial - blood; Female; Humans; Lung cancer; Lung Neoplasms - blood; Lung Neoplasms - diagnosis; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Sensitivity and Specificity; Serum mitochondrial DNA; Small Cell Lung Carcinoma - blood; Small Cell Lung Carcinoma - diagnosis; Serum mitochondrial DNA; Lung cancer; Diagnostic efficacy

The aim of the study was to investigate the clinical significance of serum mitochondrial DNA (mtDNA) in lung cancer. Serum mtDNA from 65 lung cancer patients, 20 patients with benign lung diseases and 55 healthy individuals was quantified using real-time fluorescent quantitative polymerase chain rea...