Precursor Cells in Density Fractions of Lymph Node Cells: Relation to Antibody-Producing Cells

• Published in: The Journal of immunology (1950) Vol. 105; no. 6; pp. 1522 - 1529
• Main Authors: Moav, Neomi, Harris, T. N
• Format: Journal Article
• Language: English
• Published: United States Am Assoc Immnol 01.12.1970
• Subjects: Animals; Antibodies - analysis; Antibody Formation; Antibody-Producing Cells; Centrifugation, Density Gradient; Erythrocytes - immunology; Hemagglutination Tests; Hemolytic Plaque Technique; Lymph Nodes - immunology; Mice; Radiation Effects; Spleen - immunology

Abstract Spleen cells of mice were transferred intravenously into x-irradiated syngeneic recipients which were also injected with sheep red blood cells (SRBC). The dose of irradiation was sufficient to prevent active immunization by the SRBC injected. At intervals thereafter, spleens of recipients w...