Neuroproteomics and Systems Biology Approach to Identify Temporal Biomarker Changes Post Experimental Traumatic Brain Injury in Rats

• Published in: Frontiers in neurology Vol. 7; p. 198
• Main Authors: Kobeissy, Firas H., Guingab-Cagmat, Joy D., Zhang, Zhiqun, Moghieb, Ahmed, Glushakova, Olena Y., Mondello, Stefania, Boutté, Angela M., Anagli, John, Rubenstein, Richard, Bahmad, Hisham, Wagner, Amy K., Hayes, Ronald L., Wang, Kevin K. W.
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 22.11.2016
• Subjects: biomarker; controlled cortical impact; Inflammation; Neuroscience; Oxidative Stress; Proteomics; Traumatic Brain Injury; controlled cortical impact; proteomics; inflammation; traumatic brain injury; biomarker; prognosis and therapeutics; oxidative stress

Traumatic brain injury (TBI) represents a critical health problem of which diagnosis, management, and treatment remain challenging. TBI is a contributing factor in approximately one-third of all injury-related deaths in the United States. The Centers for Disease Control and Prevention estimate that...