Antinucleosome Antibodies and Systemic Lupus Erythematosus

• Published in: Annals of the New York Academy of Sciences Vol. 1109; no. 1; pp. 421 - 428
• Main Authors: DÜZGÜN, NURŞEN, ŞAHIN, MEHMET, GENÇ, YASEMIN, TUTKAK, HÜSEYIN
• Format: Journal Article
• Language: English
• Published: Malden, USA Blackwell Publishing Inc 01.08.2007
• Subjects: Adolescent; Adult; anti-dsDNA antibody; Antibodies - blood; Antibodies - immunology; antinucleosome antibody; disease activity; DNA - immunology; Female; Humans; Kidney - immunology; Kidney - metabolism; Lupus Erythematosus, Systemic - blood; Lupus Erythematosus, Systemic - epidemiology; Lupus Erythematosus, Systemic - immunology; Male; Middle Aged; Nucleosomes - immunology; Prevalence; systemic lupus erythematosus

:  The aim of this study is to investigate the prevalence of antinucleosome antibody in systemic lupus erythematosus (SLE) and their association with disease activity and renal involvement. The study included 131 patients with SLE, 74 rheumatoid arthritis, 26 systemic sclerosis, and 50 healthy indiv...