Rapid fall in circulating non‐classical monocytes in ST elevation myocardial infarction patients correlates with cardiac injury

• Published in: The FASEB journal Vol. 35; no. 5; pp. e21604 - n/a
• Main Authors: Marsh, Sarah A., Park, Catherine, Redgrave, Rachael E., Singh, Esha, Draganova, Lilia, Boag, Stephen E., Spray, Luke, Ali, Simi, Spyridopoulos, Ioakim, Arthur, Helen M.
• Format: Journal Article
• Language: English
• Published: United States 01.05.2021
• Subjects: animal models; Animals; coronary circulation; Female; Heart Injuries - blood; Heart Injuries - etiology; Heart Injuries - pathology; Humans; Male; Mice; Middle Aged; monocytes; Monocytes - pathology; myocardial infarction; Prospective Studies; Retrospective Studies; ST Elevation Myocardial Infarction - complications; coronary circulation; monocytes; animal models; myocardial infarction

Myocardial infarction leads to a rapid innate immune response that is ultimately required for repair of damaged heart tissue. We therefore examined circulating monocyte dynamics immediately after reperfusion of the culprit coronary vessel in STEMI patients to determine whether this correlated with l...