The PD‐1/PD‐L1 axis may be aberrantly activated in occupational cholangiocarcinoma - Sato, Yasunori; Kinoshita, Masahiko; Takemura, Shigekazu; Tanaka, Shogo; Hamano, Genya; Nakamori, Shoji; Fujikawa, Masahiro; Sugawara, Yasuhiko; Yamamoto, Takatsugu; Arimoto, Akira; Yamamura, Minako; Sasaki, Motoko; et al. (Pathology international, 2017)
Keywords: Aberration; Adult; Aged; Apoptosis; Apoptosis - physiology; B7-H1 Antigen - analysis; B7-H1 Antigen - biosynthesis; Bile; Bile Duct Neoplasms - chemically induced; Bile Duct Neoplasms - immunology; Bile Duct Neoplasms - pathology; Bile ducts; CD163 antigen; CD3 antigen; CD8 antigen; Cholangiocarcinoma; Cholangiocarcinoma - chemically induced; Cholangiocarcinoma - immunology; Cholangiocarcinoma - pathology; Female; Humans; immune escape; Immunohistochemistry; In Situ Nick-End Labeling; Japan; Lesions; Leukocytes (mononuclear); Lymphocytes; Lymphocytes T; Lymphocytes, Tumor-Infiltrating - immunology; Macrophages; Male; Middle Aged; Mortality; multistep carcinogenesis; Neoplasia; occupational cholangiocarcinoma; Occupational diseases; Occupational Diseases - etiology; Occupational Diseases - immunology; Occupational Diseases - pathology; Occupational Exposure - adverse effects; organic solvent exposure; Outbreaks; PD-1 protein; PD-L1 protein; Precancerous Conditions - pathology; Printing; Programmed Cell Death 1 Receptor - analysis; Programmed Cell Death 1 Receptor - biosynthesis; Solvents - adverse effects; multistep carcinogenesis; immune escape; organic solvent exposure; occupational cholangiocarcinoma