Expression Profiles of Vpx/Vpr Proteins Are Co-related with the Primate Lentiviral Lineage

• Published in: Frontiers in microbiology Vol. 7; p. 1211
• Main Authors: Sakai, Yosuke, Miyake, Ariko, Doi, Naoya, Sasada, Hikari, Miyazaki, Yasuyuki, Adachi, Akio, Nomaguchi, Masako
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 03.08.2016
• Subjects: HIV-2; Microbiology; PPM; SIV; Vpr; Vpx; SIV; Vpr; HIV-2; PPM; Vpx

Viruses of human immunodeficiency virus type 2 (HIV-2) and some simian immunodeficiency virus (SIV) lineages carry a unique accessory protein called Vpx. Vpx is essential or critical for viral replication in natural target cells such as macrophages and T lymphocytes. We have previously shown that a...