Association of acute phase protein-haptoglobin, and epithelial-mesenchymal transition in buccal cancer: a preliminary report

• Published in: Clinical chemistry and laboratory medicine Vol. 51; no. 2; pp. 429 - 437
• Main Authors: Lee, Ching-Chih, Ho, Hsu-Chueh, Chien, Sou-Hsin, Hsiao, Shih-Hsuan, Hung, Shih-Kai, Huang, Tze-Ta, Yu, Chih-Chia, Chang, Shu-Mei, Huang, Huai-Huei, Su, Yu-Chieh
• Format: Journal Article
• Language: English
• Published: Germany De Gruyter 01.02.2013; Walter De Gruyter & Company
• Subjects: Acute phase proteins; Adult; Aged; Aged, 80 and over; buccal cancer; Cancer; Cell Line, Tumor; Cell Movement; Cheek - pathology; Epithelial-Mesenchymal Transition; Female; Haptoglobin; Haptoglobins - biosynthesis; Health hazards; Humans; IL-6; Immunohistochemistry; Interleukin 6; Interleukin-6 - pharmacology; Male; Mesenchyme; Metastases; Middle Aged; Mouth Neoplasms - metabolism; Mouth Neoplasms - pathology; Oral cancer; Patients; Phenotypes; Proportional Hazards Models; Proteins; recurrence; Statistical models; Stimulation; Tumor cell lines; Vimentin; Vimentin - biosynthesis; Western blotting

The aim of this study was to determine the influence of inflammation on acute phase protein and epithelial-mesenchymal transition (EMT) in buccal cancer. Western blotting was carried out to investigate the expression of haptoglobin and epithelial-mesenchymal transition in oral cancer cell lines with...