Effects of preimplantation genetic testing for aneuploidy on embryo transfer outcomes in women of advanced reproductive age with no more than three retrieved oocytes

• Published in: Fertility and sterility Vol. 123; no. 6; pp. 991 - 998
• Main Authors: Ou, Zhanhui, Liu, Nengqing, Chen, Ang, Li, Qingni, Li, Jieliang, Wen, Xiaojun, Huo, Junye, Fang, Xiaowu, Du, Jing, Lin, Xiufeng
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.06.2025
• Subjects: Adult; advanced reproductive age; Aneuploidy; clinical outcomes; Embryo Transfer - methods; Female; Genetic Testing - methods; Humans; Live Birth - epidemiology; live birth rate per retrieval; Maternal Age; Oocyte Retrieval; Ovarian Reserve; Pregnancy; Pregnancy Rate; Preimplantation Diagnosis - methods; Preimplantation genetic testing; Retrospective Studies; Treatment Outcome; Preimplantation genetic testing; aneuploidy; clinical outcomes; live birth rate per retrieval; advanced reproductive age
• ISSN: 0015-0282; 1556-5653; 1556-5653
• DOI: 10.1016/j.fertnstert.2024.12.010

To evaluate whether preimplantation genetic testing for aneuploidy (PGT-A) benefits women of advanced reproductive age (≥38 years old) with a diminished ovarian reserve (not more than three retrieved oocytes). A retrospective analysis comparing two groups: (a) PGT-A group: women who chose PGT-A and...