KCNQ1 Variants Associate with Type 2 Diabetes in Malaysian Malay Subjects

• Published in: Annals of the Academy of Medicine, Singapore Vol. 40; no. 11; pp. 488 - 492
• Main Authors: Saif-Ali, Riyadh, Muniandy, Sekaran, Al-Hamodi, Zaid, Lee, Cheng Siang, Ahmed, Khaled A, Al-Mekhlafi, Abdulsalam M, Ismail, Ikram Shah
• Format: Journal Article
• Language: English
• Published: Singapore 01.11.2011
• Subjects: Adult; Diabetes Mellitus, Type 2 - ethnology; Diabetes Mellitus, Type 2 - genetics; Female; Genetics, Population; Haplotypes - genetics; Humans; KCNQ1 Potassium Channel - genetics; Malaysia; Male; Middle Aged; Polymorphism, Single Nucleotide - genetics; Sequence Analysis, DNA; Malaysia

Introduction: Type 2 diabetes (T2D) candidate gene: potassium voltage-gated channel, KQT-like subfamily, member 1 (KCNQ1) was suggested by conducting a genome wide association study (GWAS) in Japanese population. Association studies have been replicated among East Asian populations; however, the ass...