Demonstration and characterization of phosphate transport in mammalian peroxisomes

• Published in: Biochemical journal Vol. 389; no. Pt 3; pp. 717 - 722
• Main Authors: Visser, Wouter F, Van Roermund, Carlo W, Ijlst, Lodewijk, Hellingwerf, Klaas J, Wanders, Ronald J A, Waterham, Hans R
• Format: Journal Article
• Language: English
• Published: England Portland Press Ltd 01.08.2005
• Subjects: Animals; Biological Transport, Active; Carrier Proteins - metabolism; Cattle; Diphosphates - metabolism; Kidney; Kinetics; Peroxisomes - metabolism; Phosphates - metabolism

It is now well established that the peroxisomal membrane is not freely permeable to small molecules in vivo, which implies the existence of metabolite transporters in the peroxisomal membrane. A few putative peroxisomal metabolite transporters have indeed been identified, but the function of these p...