Protein kinase C-dependent NF-κB activation is altered in T cells by chronic stress

• Published in: Cellular and molecular life sciences : CMLS Vol. 62; no. 15; pp. 1744 - 1754
• Main Authors: Silberman, D. M., Zorrilla-Zubilete, M., Cremaschi, G. A., Genaro, A. M.
• Format: Journal Article
• Language: English
• Published: Basel Birkhäuser-Verlag 01.08.2005

Chronic stress has been associated with impaired immune function. In this work we studied the effect of chronic mild stress (CMS) exposure on the early intracellular pathways involved in T cells after stimulation with mitogen. We found that mitogen stimulation of T lymphocytes from CMS-exposed mice...