Evidence for Close Linkage of a Mouse Light Chain Marker with the LY-2,3 Locus

• Published in: The Journal of immunology (1950) Vol. 121; no. 4; pp. 1585 - 1590
• Main Authors: Gibson, David M, Taylor, Benjamin A, Cherry, Marianna
• Format: Journal Article
• Language: English
• Published: United States Am Assoc Immnol 01.10.1978
• Subjects: Animals; Chromosome Mapping; Female; Genetic Linkage; Immunoglobulin Light Chains - genetics; Isoelectric Focusing; Male; Mice; Mice, Inbred A; Mice, Inbred AKR; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Inbred DBA; Mice, Inbred NZB

Light chains associated with normal serum immunoglobulin can be resolved into a finite number of discrete focusing bands by isoelectric focusing. Four distinct light chain patterns can be distinguished among the inbred mouse strains. In the present studies inheritance of the characteristic light cha...