Identification of small fiber neuropathy in neuronal intranuclear inclusion disease: A clinicopathological study

• Published in: Alzheimer's & dementia Vol. 21; no. 2; pp. e14596 - n/a
• Main Authors: Liu, Minglei, Liu, Ruoyu, Yuan, Yanpeng, Liu, Xiaojing, Li, Lanjun, Wang, Yangyang, Yuan, Jing, Zhang, Ke, Li, Shuo, Yang, Ting, Wang, Yanlin, Gao, Yuan, Liu, Han, Xue, Yinge, Cheng, Lin, Yang, Tianyuan, Kong, Ying, Liu, Chen, Wang, Yanjiang, Xu, Yuming, Yang, Jing
• Format: Journal Article
• Language: English
• Published: United States John Wiley and Sons Inc 01.02.2025
• Subjects: Aged; Aged, 80 and over; Alzheimer Disease - pathology; autonomic dysfunction; dementia; Female; Humans; intraepidermal nerve fiber density; Intranuclear Inclusion Bodies - pathology; Male; Middle Aged; Nerve Fibers - pathology; Neurodegenerative Diseases - complications; Neurodegenerative Diseases - pathology; neuronal intranuclear inclusion disease; Parkinson Disease - pathology; skin biopsy; small fiber neuropathy; Small Fiber Neuropathy - diagnosis; Small Fiber Neuropathy - etiology; Small Fiber Neuropathy - pathology; small fiber neuropathy; dementia; intraepidermal nerve fiber density; autonomic dysfunction; skin biopsy; neuronal intranuclear inclusion disease

INTRODUCTION Neuronal intranuclear inclusion disease (NIID) manifests as dementia combined with other neurological symptoms. However, small fiber neuropathy (SFN) and pathology remain unknown in NIID. METHODS A total of 294 subjects, including patients with NIID, Parkinson's disease, Alzheimer&...