Bioaccumulation and in vivo fate of toxic benzylalkyldimethylammonium chloride in rats via the radiotracer analysis

• Published in: Chemosphere (Oxford) Vol. 338; p. 139460
• Main Authors: Park, Jung Eun, Ryu, Seung-Hun, Ito, Satoshi, Song, Mi-Kyung, Gu, Eun Ji, Shin, Hyunil, Kim, Young-Hee, Jeon, Jongho
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.10.2023
• Subjects: adrenal glands; ammonium compounds; animals; autoradiography; Benzylalkyldimethylammonium chloride; bioaccumulation; Biological uptake; chlorides; COVID-19 infection; excretion; heart; In vivo assessment; inhalation exposure; intravenous injection; lungs; males; pancreas; Quantitative whole-body autoradiography; quaternary ammonium compounds; radioactivity; radiolabeling; Radiotracer; toxicity; Quantitative whole-body autoradiography; In vivo assessment; Benzylalkyldimethylammonium chloride; Radiotracer; Biological uptake

Benzylalkyldimethylammonium chloride (BAC), a quaternary ammonium compound (QAC), is utilized in industrial and biomedical applications for antimicrobial purposes. Since the coronavirus disease (COVID-19) outbreak, various types of BAC-containing household chemicals have been produced. BACs have sev...