Serum Inflammatory Markers in Obstructive Sleep Apnea: A Meta-Analysis

• Published in: Journal of clinical sleep medicine Vol. 9; no. 10; pp. 1003 - 1012
• Main Authors: Nadeem, Rashid, Molnar, Janos, Madbouly, Essam M., Nida, Mahwish, Aggarwal, Saurabh, Sajid, Hassan, Naseem, Jawed, Loomba, Rohit
• Format: Journal Article
• Language: English
• Published: United States American Academy of Sleep Medicine 15.10.2013
• Subjects: Adult; Aged; Biomarkers - blood; C-Reactive Protein - analysis; C-Reactive Protein - metabolism; Cell Adhesion Molecules - analysis; Cell Adhesion Molecules - metabolism; Disease Progression; Female; Humans; Inflammation Mediators - blood; Interleukin-6 - blood; Interleukin-8 - blood; Male; Middle Aged; New Research; Polysomnography - methods; Selectins - analysis; Selectins - metabolism; Sensitivity and Specificity; Severity of Illness Index; Sleep Apnea, Obstructive - blood; Sleep Apnea, Obstructive - diagnosis; Tumor Necrosis Factor-alpha - analysis; Tumor Necrosis Factor-alpha - metabolism; CRP; VCAM; inflammatory markers; ICAM; TNF-α; Selectins; IL-8; Obstructive sleep apnea; IL-6

Obstructive sleep apnea (OSA) has been linked to and is associated with increased cardiovascular and cerebrovascular morbidity. Ongoing inflammatory responses play an important role in this association. Multiple small size studies addressing the profile of the inflammatory markers in OSA are availab...