Quantification of lipoproteins by proton nuclear magnetic resonance spectroscopy (1H-NMRS) improves the prediction of cardiac autonomic dysfunction in patients with type 1 diabetes

• Published in: Journal of endocrinological investigation Vol. 47; no. 8; pp. 2075 - 2085
• Main Authors: Nattero-Chávez, L., Insenser, M., Amigó, N., Samino, S., Martínez-Micaelo, N., Dorado Avendaño, B., Quintero Tobar, A., Escobar-Morreale, H. F., Luque-Ramírez, M.
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.08.2024; Springer Nature B.V
• Subjects: Autonomic nervous system; C-reactive protein; Cholesterol; D-Galactosamine; Diabetes; Diabetes mellitus (insulin dependent); Diabetic neuropathy; Endocrinology; Fibrinogen; Glycoproteins; High density lipoprotein; Internal Medicine; Lipoproteins; Magnetic resonance spectroscopy; Medicine; Medicine & Public Health; Metabolic Diseases; N-Acetylglucosamine; Neuropathy; NMR; Nuclear magnetic resonance; Original Article; Prediction models; Spectrum analysis; Statistical analysis; Triglycerides; Tumor necrosis factor-α; Glycoprotein profile; Lipoproteins; Autonomic nervous system; Type 1 diabetes; Proton nuclear magnetic resonance spectroscopy; Lipid profile; Triglycerides; Cardioautonomic neuropathy

Aims To assess if advanced characterization of serum glycoprotein and lipoprotein profile, measured by proton nuclear magnetic resonance spectroscopy ( 1 H-NMRS) improves a predictive clinical model of cardioautonomic neuropathy (CAN) in subjects with type 1 diabetes (T1D). Methods Cross-sectional s...