Update on the management of fungal keratitis
Purpose The aim of this article is to introduce the recent advance on the studies of fungal keratitis published over past 5 years. Methods We performed literature review of articles published on PubMed, Google Scholar, CNKI and Web of Science relevant to the diagnosis, pathogenesis and novel treatme...
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Published in | International ophthalmology Vol. 41; no. 9; pp. 3249 - 3256 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
Dordrecht
Springer Netherlands
01.09.2021
Springer Nature B.V |
Subjects | |
Online Access | Get full text |
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Abstract | Purpose
The aim of this article is to introduce the recent advance on the studies of fungal keratitis published over past 5 years.
Methods
We performed literature review of articles published on PubMed, Google Scholar, CNKI and Web of Science relevant to the diagnosis, pathogenesis and novel treatment of fungal keratitis.
Results
Excessive inflammation can lead to stromal damage and corneal opacification, hence the research on immune mechanism provides many potential therapeutic targets for fungal keratitis. Many researchers discussed the importance of earlier definitive diagnosis and were trying to find rapid and accurate diagnostic methods of pathogens. Develop new drug delivery systems and new routes of administration with better corneal penetration, prolonged ocular residence time, and better mucoadhesive properties is also one of the research hotspots. Additionally, many novel therapeutic agents and methods have been gradually applied in clinical ophthalmology.
Conclusion
The diagnosis and treatment of fungal keratitis are still a challenge for ophthalmologist, and many researches provide new methods to conquer these problems. |
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AbstractList | The aim of this article is to introduce the recent advance on the studies of fungal keratitis published over past 5 years.PURPOSEThe aim of this article is to introduce the recent advance on the studies of fungal keratitis published over past 5 years.We performed literature review of articles published on PubMed, Google Scholar, CNKI and Web of Science relevant to the diagnosis, pathogenesis and novel treatment of fungal keratitis.METHODSWe performed literature review of articles published on PubMed, Google Scholar, CNKI and Web of Science relevant to the diagnosis, pathogenesis and novel treatment of fungal keratitis.Excessive inflammation can lead to stromal damage and corneal opacification, hence the research on immune mechanism provides many potential therapeutic targets for fungal keratitis. Many researchers discussed the importance of earlier definitive diagnosis and were trying to find rapid and accurate diagnostic methods of pathogens. Develop new drug delivery systems and new routes of administration with better corneal penetration, prolonged ocular residence time, and better mucoadhesive properties is also one of the research hotspots. Additionally, many novel therapeutic agents and methods have been gradually applied in clinical ophthalmology.RESULTSExcessive inflammation can lead to stromal damage and corneal opacification, hence the research on immune mechanism provides many potential therapeutic targets for fungal keratitis. Many researchers discussed the importance of earlier definitive diagnosis and were trying to find rapid and accurate diagnostic methods of pathogens. Develop new drug delivery systems and new routes of administration with better corneal penetration, prolonged ocular residence time, and better mucoadhesive properties is also one of the research hotspots. Additionally, many novel therapeutic agents and methods have been gradually applied in clinical ophthalmology.The diagnosis and treatment of fungal keratitis are still a challenge for ophthalmologist, and many researches provide new methods to conquer these problems.CONCLUSIONThe diagnosis and treatment of fungal keratitis are still a challenge for ophthalmologist, and many researches provide new methods to conquer these problems. The aim of this article is to introduce the recent advance on the studies of fungal keratitis published over past 5 years. We performed literature review of articles published on PubMed, Google Scholar, CNKI and Web of Science relevant to the diagnosis, pathogenesis and novel treatment of fungal keratitis. Excessive inflammation can lead to stromal damage and corneal opacification, hence the research on immune mechanism provides many potential therapeutic targets for fungal keratitis. Many researchers discussed the importance of earlier definitive diagnosis and were trying to find rapid and accurate diagnostic methods of pathogens. Develop new drug delivery systems and new routes of administration with better corneal penetration, prolonged ocular residence time, and better mucoadhesive properties is also one of the research hotspots. Additionally, many novel therapeutic agents and methods have been gradually applied in clinical ophthalmology. The diagnosis and treatment of fungal keratitis are still a challenge for ophthalmologist, and many researches provide new methods to conquer these problems. PurposeThe aim of this article is to introduce the recent advance on the studies of fungal keratitis published over past 5 years.MethodsWe performed literature review of articles published on PubMed, Google Scholar, CNKI and Web of Science relevant to the diagnosis, pathogenesis and novel treatment of fungal keratitis.ResultsExcessive inflammation can lead to stromal damage and corneal opacification, hence the research on immune mechanism provides many potential therapeutic targets for fungal keratitis. Many researchers discussed the importance of earlier definitive diagnosis and were trying to find rapid and accurate diagnostic methods of pathogens. Develop new drug delivery systems and new routes of administration with better corneal penetration, prolonged ocular residence time, and better mucoadhesive properties is also one of the research hotspots. Additionally, many novel therapeutic agents and methods have been gradually applied in clinical ophthalmology.ConclusionThe diagnosis and treatment of fungal keratitis are still a challenge for ophthalmologist, and many researches provide new methods to conquer these problems. Purpose The aim of this article is to introduce the recent advance on the studies of fungal keratitis published over past 5 years. Methods We performed literature review of articles published on PubMed, Google Scholar, CNKI and Web of Science relevant to the diagnosis, pathogenesis and novel treatment of fungal keratitis. Results Excessive inflammation can lead to stromal damage and corneal opacification, hence the research on immune mechanism provides many potential therapeutic targets for fungal keratitis. Many researchers discussed the importance of earlier definitive diagnosis and were trying to find rapid and accurate diagnostic methods of pathogens. Develop new drug delivery systems and new routes of administration with better corneal penetration, prolonged ocular residence time, and better mucoadhesive properties is also one of the research hotspots. Additionally, many novel therapeutic agents and methods have been gradually applied in clinical ophthalmology. Conclusion The diagnosis and treatment of fungal keratitis are still a challenge for ophthalmologist, and many researches provide new methods to conquer these problems. |
Author | Zhong, Jing-Xiang Shi, Qi Sha, Xiao-Yuan Liu, Lian |
Author_xml | – sequence: 1 givenname: Xiao-Yuan surname: Sha fullname: Sha, Xiao-Yuan organization: Department of Ophthalmology, First Affiliated Hospital of Jinan University – sequence: 2 givenname: Qi surname: Shi fullname: Shi, Qi organization: Department of Ophthalmology, First Affiliated Hospital of Jinan University – sequence: 3 givenname: Lian surname: Liu fullname: Liu, Lian email: liulianbb@163.com organization: Department of Ophthalmology, First Affiliated Hospital of Jinan University – sequence: 4 givenname: Jing-Xiang surname: Zhong fullname: Zhong, Jing-Xiang organization: Department of Ophthalmology, First Affiliated Hospital of Jinan University |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/33929644$$D View this record in MEDLINE/PubMed |
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Keywords | Drug delivery systems Therapeutic keratoplasty Fungal keratitis Immune mechanism |
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The aim of this article is to introduce the recent advance on the studies of fungal keratitis published over past 5 years.
Methods
We performed... The aim of this article is to introduce the recent advance on the studies of fungal keratitis published over past 5 years. We performed literature review of... PurposeThe aim of this article is to introduce the recent advance on the studies of fungal keratitis published over past 5 years.MethodsWe performed literature... The aim of this article is to introduce the recent advance on the studies of fungal keratitis published over past 5 years.PURPOSEThe aim of this article is to... |
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SubjectTerms | Autophagy Chemical compounds Cornea Cytokines Diagnosis Drug delivery Drug delivery systems Epidemiology Fungi Infections Inflammation Keratitis Literature reviews Medicine Medicine & Public Health Neutrophils Ophthalmology Pathogenesis Pathogens Pharmacology Reagents Review Therapeutic targets Ulcers |
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Title | Update on the management of fungal keratitis |
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