Characteristics and risk factors for Pneumocystis jirovecii pneumonia in patients with idiopathic membranous nephropathy

• Published in: European journal of clinical microbiology & infectious diseases Vol. 40; no. 11; pp. 2305 - 2314
• Main Authors: Yang, Lie, Xia, Peng, Zhou, Yangzhong, Cui, Quexuan, Chen, Gang, Zheng, Ke, Qin, Yan, Li, Xuemei
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.11.2021; Springer Nature B.V
• Subjects: Adrenal Cortex Hormones - administration & dosage; Adult; Anti-Inflammatory Agents - administration & dosage; Biomedical and Life Sciences; Biomedicine; China - epidemiology; Corticoids; Corticosteroids; Cyclophosphamide; Epidermal growth factor receptors; Fatalities; Female; Glomerular filtration rate; Glomerular Filtration Rate - drug effects; Glomerulonephritis, Membranous - complications; Glomerulonephritis, Membranous - drug therapy; Glomerulonephritis, Membranous - physiopathology; Humans; Immunosuppressive agents; Infections; Internal Medicine; L-Lactate dehydrogenase; Lactate dehydrogenase; Lactic acid; Male; Medical Microbiology; Medical prognosis; Membranous nephropathy; Middle Aged; Mortality; Multivariate analysis; Nephropathy; Observational studies; Opportunist infection; Original Article; Patients; Pneumocystis carinii - genetics; Pneumocystis carinii - physiology; Pneumocystis jirovecii; Pneumonia; Pneumonia, Pneumocystis - epidemiology; Pneumonia, Pneumocystis - etiology; Pneumonia, Pneumocystis - microbiology; Pneumonia, Pneumocystis - physiopathology; Prednisone; Prednisone - administration & dosage; Prognosis; Proteinuria; Regression analysis; Retrospective Studies; Risk analysis; Risk Factors; Steroids; Ventilation; China; Pneumonia; Immunosuppression; Corticosteroids; Membranous nephropathy; Pneumocystis jirovecii

Pneumocystis jirovecii pneumonia (PCP) is a life-threatening opportunistic infection in idiopathic membranous nephropathy (IMN) patients, who are treated with immunosuppressive drugs. However, the risk factors of infection and their prognosis are rarely investigated. We aimed to characterize the cli...