PHD2 attenuates high-glucose-induced blood retinal barrier breakdown in human retinal microvascular endothelial cells by regulating the Hif-1α/VEGF pathway - Li, Jia; Lu, Xi; Wei, Liqing; Ye, Dan; Lin, Jianqiang; Tang, Xiaoyu; Cui, Kaixuan; Yu, Shanshan; Xu, Yue; Liang, Xiaoling (Inflammation research, 2022)
Keywords: Allergology; Angiogenesis; Biomedical and Life Sciences; Biomedicine; Blood; Breakdown; Cell viability; Dermatology; Diabetes mellitus; Diacylglycerol kinase; Edema; Electrical resistance; Electrical resistivity; Endothelial cells; Enzyme-linked immunosorbent assay; Growth factors; Hydroxylase; Hyperglycemia; Hypoxia; Hypoxia-inducible factor 1; Hypoxia-inducible factor 1a; Immunofluorescence; Immunology; Investigations; Kinases; Microvasculature; Neurology; Original Research Article; Pathogenesis; Permeability; Pharmacology/Toxicology; Proteins; Retina; Reverse transcription; Rheumatology; Vascular endothelial growth factor; Zonula occludens-1 protein; Hyperglycemia; Hypoxia-inducible factor 1α; Prolyl-4-hydroxylase 2; Tight junction; Blood–retinal barrier; Retinal inflammation; Vascular endothelial growth factor