Intermittent normobaric hypoxia facilitates high altitude acclimatization by curtailing hypoxia-induced inflammation and dyslipidemia

• Published in: Pflügers Archiv Vol. 471; no. 7; pp. 949 - 959
• Main Authors: Gangwar, Anamika, Pooja, Sharma, Manish, Singh, Krishan, Patyal, Anita, Bhaumik, Gopinath, Bhargava, Kalpana, Sethy, Niroj Kumar
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.07.2019; Springer Nature B.V
• Subjects: Acclimatization; Acclimatization - physiology; Acute phase proteins; Acyltransferase; Adult; Altitude; Altitude Sickness - metabolism; Altitude Sickness - physiopathology; Amyloid; Apolipoproteins; Biomedical and Life Sciences; Biomedicine; C-reactive protein; Cell Biology; Cholesterol; Cholesterol Ester Transfer Proteins - metabolism; Cholesteryl ester transfer protein; Dyslipidemia; Dyslipidemias - metabolism; Dyslipidemias - physiopathology; Female; Fibrinogen; High density lipoprotein; Human Physiology; Humans; Hypoxia; Hypoxia - metabolism; Hypoxia - physiopathology; Inflammation; Inflammation - physiopathology; Integrative Physiology; Lecithin; Low density lipoprotein; Male; Metabolic disorders; Molecular Medicine; Neurosciences; Phosphatidylcholine-Sterol O-Acyltransferase - metabolism; Phospholipid transfer protein; Phospholipid Transfer Proteins - metabolism; Phospholipids; Proteins; Proteomics; Receptors; Young Adult; Intermittent hypoxia; High altitude; Inflammation; Apolipoproteins; Dyslipidemia

Intermittent hypoxic training (IHT) is a discrete cost-effective method for improving athletic performance and high altitude acclimatization. Unfortunately, IHT protocols widely vary in terms of hypoxia severity, duration, and number of cycles affecting physiological outcomes. In the present study,...